Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 3464520..3465214 Replicon chromosome
Accession NZ_CP031515
Organism Dickeya zeae strain EC2

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag DWV07_RS15405 Protein ID WP_210436452.1
Coordinates 3464520..3464918 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag DWV07_RS15410 Protein ID WP_038666391.1
Coordinates 3464921..3465214 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWV07_RS15375 3460717..3462060 - 1344 WP_168366294.1 radical SAM protein -
DWV07_RS15380 3462253..3462573 - 321 WP_168366295.1 hypothetical protein -
DWV07_RS15385 3462679..3462948 - 270 Protein_3001 hypothetical protein -
DWV07_RS15390 3463469..3463717 - 249 WP_168366296.1 helix-turn-helix domain-containing protein -
DWV07_RS15395 3463817..3464083 + 267 WP_168366297.1 helix-turn-helix domain-containing protein -
DWV07_RS15400 3464152..3464418 + 267 WP_168366298.1 helix-turn-helix domain-containing protein -
DWV07_RS15405 3464520..3464918 - 399 WP_210436452.1 type II toxin-antitoxin system YafO family toxin Toxin
DWV07_RS15410 3464921..3465214 - 294 WP_038666391.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
DWV07_RS15420 3465798..3467051 - 1254 WP_168366300.1 glutamate-5-semialdehyde dehydrogenase -
DWV07_RS15425 3467062..3468165 - 1104 WP_012885880.1 glutamate 5-kinase -
DWV07_RS15430 3468293..3468652 - 360 WP_168366301.1 sigma factor-binding protein Crl -
DWV07_RS15435 3468918..3470168 - 1251 WP_168366302.1 esterase FrsA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15283.56 Da        Isoelectric Point: 8.1051

>T109321 WP_210436452.1 NZ_CP031515:c3464918-3464520 [Dickeya zeae]
IRIFKSTLIRQQLSPQELDDLVADFLSYKKEGVLPDTFGRDAPYDDDRTYPLVKKEQVSHIHLADADAPFPKFLRQFKRT
SDQAHLVYCHGASDPDAYLLIIILKPEAHKMARNNNHMHKIGVMAEAFRMKY

Download         Length: 399 bp

>T109321 NZ_CP031515:c3464918-3464520 [Dickeya zeae]
ATCAGGATTTTCAAATCAACGCTTATCCGCCAGCAATTAAGCCCGCAAGAGCTGGATGATTTAGTGGCGGATTTTCTGTC
GTATAAAAAAGAGGGCGTGTTGCCGGATACCTTTGGCCGTGACGCCCCTTATGATGATGACCGAACCTATCCCCTGGTGA
AAAAAGAGCAGGTGTCGCATATTCATCTTGCTGATGCAGATGCCCCTTTCCCTAAGTTTTTACGCCAGTTCAAGCGAACC
AGCGATCAGGCCCACTTGGTGTACTGCCATGGTGCCAGTGATCCAGATGCCTACCTGCTGATTATCATCCTGAAACCCGA
AGCGCATAAGATGGCGCGAAATAATAACCACATGCACAAGATAGGTGTGATGGCCGAAGCATTCAGAATGAAGTATTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10992.43 Da        Isoelectric Point: 4.9062

>AT109321 WP_038666391.1 NZ_CP031515:c3465214-3464921 [Dickeya zeae]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEEKQGRVHTAARFRPSAERLSEIAQNG
QTLLQNASDKDLTEFSE

Download         Length: 294 bp

>AT109321 NZ_CP031515:c3465214-3464921 [Dickeya zeae]
ATGGAACGCATTCTTGCTGAAAAATCTATCAACATCACCGAGTTAAGAAAAAACCCGGCGAAGTATTTTATTGATGAACC
GGTTGCCGTTCTCTCCAACAACCGCCCGGCTGGCTACATGGTCAGCGCTAAGGTGTTTGAAGAGCTGATCGATCTGTTGG
AAGAGAAGCAGGGTAGGGTGCATACTGCTGCGCGTTTTCGTCCAAGCGCTGAACGGTTAAGCGAGATTGCGCAGAACGGC
CAGACACTGCTGCAAAACGCCTCGGACAAGGATCTGACCGAGTTCTCTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References