Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1903713..1904437 Replicon chromosome
Accession NZ_CP031514
Organism Chromobacterium sp. Rain0013

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag DXT74_RS08990 Protein ID WP_194427776.1
Coordinates 1904129..1904437 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag DXT74_RS08985 Protein ID WP_194427775.1
Coordinates 1903713..1904117 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXT74_RS08950 1898809..1899138 + 330 WP_194427769.1 hypothetical protein -
DXT74_RS08955 1899314..1899814 + 501 WP_194427770.1 hypothetical protein -
DXT74_RS08960 1900007..1900171 + 165 WP_194427771.1 DUF3892 domain-containing protein -
DXT74_RS08965 1900229..1900975 - 747 WP_194427772.1 hypothetical protein -
DXT74_RS08970 1901255..1901809 + 555 WP_194427773.1 PH domain-containing protein -
DXT74_RS08975 1901893..1902741 + 849 WP_194427774.1 hypothetical protein -
DXT74_RS08980 1902805..1903617 + 813 WP_196783849.1 hypothetical protein -
DXT74_RS08985 1903713..1904117 - 405 WP_194427775.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
DXT74_RS08990 1904129..1904437 - 309 WP_194427776.1 type II toxin-antitoxin system MqsR family toxin Toxin
DXT74_RS08995 1904477..1905493 - 1017 WP_194427777.1 hypothetical protein -
DXT74_RS09000 1905490..1905909 - 420 WP_194427778.1 hypothetical protein -
DXT74_RS09005 1905939..1906397 - 459 WP_194427779.1 hypothetical protein -
DXT74_RS09010 1906532..1907158 + 627 WP_194427780.1 SOS response-associated peptidase family protein -
DXT74_RS09015 1907184..1907675 - 492 WP_194427781.1 hypothetical protein -
DXT74_RS09020 1907689..1908945 - 1257 WP_196783890.1 Y-family DNA polymerase -
DXT74_RS09025 1908945..1909361 - 417 WP_194427783.1 translesion error-prone DNA polymerase V autoproteolytic subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1891549..1930677 39128


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-98)

Antitoxin

Cro/C1-type helix-turn-helix domain

(75-128)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11420.17 Da        Isoelectric Point: 8.2803

>T109306 WP_194427776.1 NZ_CP031514:c1904437-1904129 [Chromobacterium sp. Rain0013]
MEKRTAHYSLDEIKAAVQARGVLCFTRTARTGFVELGLSEAEALAVVQLIGRRDFNKSMTTHLDHTVWQDVYKPITPCGR
AYVKFTLRADGAIVISFKACEE

Download         Length: 309 bp

>T109306 NZ_CP031514:c1904437-1904129 [Chromobacterium sp. Rain0013]
ATGGAAAAACGCACCGCTCACTATTCTTTGGACGAAATTAAAGCTGCGGTGCAGGCTCGCGGCGTGCTCTGTTTCACCAG
AACCGCGCGAACCGGTTTTGTTGAGTTGGGCTTGAGCGAAGCGGAAGCCCTGGCCGTAGTGCAGTTGATTGGCCGGCGGG
ACTTCAACAAGTCGATGACAACCCATCTAGACCACACTGTATGGCAGGACGTGTACAAACCCATAACCCCATGTGGGCGG
GCTTACGTCAAATTCACCCTGCGCGCGGATGGCGCCATCGTTATTTCGTTCAAGGCGTGCGAGGAGTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 14929.16 Da        Isoelectric Point: 7.4162

>AT109306 WP_194427775.1 NZ_CP031514:c1904117-1903713 [Chromobacterium sp. Rain0013]
MAHHCLNCEAAEMVLETKDVTVSYKHLSAVVPAVTGWHCPHCGEIEFTDEASSRRHMDALQELAQRQRAETRFFVKATRQ
KLKLTQAAAAKIFGGGVNAFSEYERGVTQPPMATIKLLKVLDKHPDLLREVAEA

Download         Length: 405 bp

>AT109306 NZ_CP031514:c1904117-1903713 [Chromobacterium sp. Rain0013]
ATGGCGCATCATTGCCTGAATTGCGAAGCGGCCGAGATGGTTCTTGAAACCAAGGATGTCACGGTCTCCTACAAACATTT
ATCCGCGGTAGTGCCGGCGGTGACGGGCTGGCATTGTCCGCATTGCGGTGAAATCGAGTTCACCGACGAGGCCAGTTCGC
GCCGCCACATGGACGCGCTGCAGGAGCTGGCCCAGCGTCAGCGCGCCGAAACACGCTTCTTTGTGAAGGCCACCCGGCAA
AAGCTCAAGCTGACCCAGGCGGCGGCGGCCAAAATATTTGGCGGCGGCGTCAATGCGTTCAGCGAGTATGAGCGCGGCGT
GACGCAACCGCCAATGGCAACCATCAAGCTGTTGAAGGTACTGGACAAGCACCCGGACTTGCTTCGGGAAGTGGCTGAAG
CCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References