Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1911042..1911597 Replicon chromosome
Accession NZ_CP031466
Organism Paraburkholderia caffeinilytica strain CF1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DSC91_RS08490 Protein ID WP_115777716.1
Coordinates 1911042..1911293 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DSC91_RS08495 Protein ID WP_115777717.1
Coordinates 1911301..1911597 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSC91_RS08470 1906393..1907997 + 1605 WP_115777712.1 iron ABC transporter permease -
DSC91_RS08475 1908035..1909093 + 1059 WP_115777713.1 ABC transporter ATP-binding protein -
DSC91_RS08480 1909103..1909978 - 876 WP_115777714.1 LysR family transcriptional regulator -
DSC91_RS08485 1910093..1911013 + 921 WP_115777715.1 DMT family transporter -
DSC91_RS08490 1911042..1911293 - 252 WP_115777716.1 Txe/YoeB family addiction module toxin Toxin
DSC91_RS08495 1911301..1911597 - 297 WP_115777717.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DSC91_RS08500 1911870..1913168 - 1299 WP_175171994.1 MFS transporter -
DSC91_RS08505 1913365..1914138 + 774 WP_115777719.1 GntR family transcriptional regulator -
DSC91_RS08510 1914147..1915817 + 1671 WP_115777720.1 malonate decarboxylase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10032.33 Da        Isoelectric Point: 7.8446

>T109259 WP_115777716.1 NZ_CP031466:c1911293-1911042 [Paraburkholderia caffeinilytica]
MFTDEAWDDYRYWQETDRKVLRKINTLLEECRRDPYRGTGKPEALVGSLSGFWSRRITHADRLVYLPRDGKIYVIACRFH
YDD

Download         Length: 252 bp

>T109259 NZ_CP031466:c1911293-1911042 [Paraburkholderia caffeinilytica]
ATGTTCACCGATGAAGCATGGGACGACTATCGGTATTGGCAGGAAACCGATCGCAAAGTCTTACGCAAGATCAATACGCT
GCTTGAGGAGTGCCGGCGCGATCCTTATCGCGGCACTGGAAAACCGGAGGCGCTGGTCGGCAGCTTGAGCGGGTTCTGGT
CGCGCCGTATCACGCACGCTGATCGCCTGGTCTATTTGCCGCGAGACGGAAAGATTTACGTGATCGCCTGCCGTTTCCAC
TACGACGACTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10844.26 Da        Isoelectric Point: 6.9790

>AT109259 WP_115777717.1 NZ_CP031466:c1911597-1911301 [Paraburkholderia caffeinilytica]
MNVLTYSEARAGFKQAMDDVCRDHTPMLITRQSGENVVMVSLEDFNAMQETLYLLSSSKNAQRLARSIAQLNAGSALPRE
LLTDEQTEKPQRGGRKGG

Download         Length: 297 bp

>AT109259 NZ_CP031466:c1911597-1911301 [Paraburkholderia caffeinilytica]
ATGAACGTCCTTACTTACAGCGAGGCGCGTGCCGGCTTCAAGCAAGCGATGGACGACGTCTGCCGCGATCACACGCCCAT
GCTGATAACCAGACAGAGTGGCGAAAATGTGGTGATGGTTTCGCTCGAGGATTTCAATGCGATGCAAGAAACCTTGTATC
TTCTGAGTTCTTCGAAGAATGCCCAGCGGCTCGCCAGGTCTATCGCCCAGTTGAATGCCGGCAGTGCGTTGCCGCGCGAA
CTGCTGACCGATGAACAAACAGAGAAGCCGCAACGAGGAGGCCGCAAAGGCGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References