Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4720529..4721118 Replicon chromosome
Accession NZ_CP031461
Organism Xanthomonas oryzae pv. oryzae strain OS198

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag BRN32_RS23665 Protein ID WP_011260747.1
Coordinates 4720837..4721118 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BRN32_RS23660 Protein ID WP_011260746.1
Coordinates 4720529..4720819 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRN32_RS23620 (BRN32_23620) 4715673..4716281 - 609 WP_011409746.1 DUF4123 domain-containing protein -
BRN32_RS23625 (BRN32_23625) 4716284..4716706 - 423 WP_042465811.1 PAAR domain-containing protein -
BRN32_RS23630 (BRN32_23630) 4716834..4717160 - 327 WP_228329596.1 hypothetical protein -
BRN32_RS23640 (BRN32_23640) 4717415..4717747 + 333 WP_011260743.1 hypothetical protein -
BRN32_RS25725 4717907..4718094 + 188 Protein_4281 hypothetical protein -
BRN32_RS23650 (BRN32_23650) 4718197..4719591 - 1395 WP_027703652.1 type III secretion system effector XopQ -
BRN32_RS23660 (BRN32_23660) 4720529..4720819 - 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
BRN32_RS23665 (BRN32_23665) 4720837..4721118 - 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BRN32_RS23670 (BRN32_23670) 4721213..4723465 - 2253 WP_075243583.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11070.83 Da        Isoelectric Point: 10.2139

>T109244 WP_011260747.1 NZ_CP031461:c4721118-4720837 [Xanthomonas oryzae pv. oryzae]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T109244 NZ_CP031461:c4721118-4720837 [Xanthomonas oryzae pv. oryzae]
ATGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCAGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT109244 WP_011260746.1 NZ_CP031461:c4720819-4720529 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT109244 NZ_CP031461:c4720819-4720529 [Xanthomonas oryzae pv. oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References