Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1168557..1169211 Replicon chromosome
Accession NZ_CP031396
Organism Pseudomonas protegens strain FD6

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DWF74_RS04955 Protein ID WP_019092839.1
Coordinates 1168557..1168907 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DWF74_RS04960 Protein ID WP_102864712.1
Coordinates 1168894..1169211 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWF74_RS04945 1165316..1166848 + 1533 WP_011062195.1 NADH-quinone oxidoreductase subunit M -
DWF74_RS04950 1166856..1168319 + 1464 WP_015636299.1 NADH-quinone oxidoreductase subunit NuoN -
DWF74_RS04955 1168557..1168907 + 351 WP_019092839.1 hypothetical protein Toxin
DWF74_RS04960 1168894..1169211 + 318 WP_102864712.1 transcriptional regulator Antitoxin
DWF74_RS04965 1169280..1170662 - 1383 WP_102864711.1 cysteine--tRNA ligase -
DWF74_RS04970 1170681..1172381 - 1701 WP_115580500.1 glutamine--tRNA ligase/YqeY domain fusion protein -
DWF74_RS04975 1172652..1173155 + 504 WP_016965727.1 peptidyl-prolyl cis-trans isomerase -
DWF74_RS04980 1173152..1173904 + 753 WP_102864709.1 UDP-2,3-diacylglucosamine diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(48-101)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13980.08 Da        Isoelectric Point: 8.9805

>T109172 WP_019092839.1 NZ_CP031396:1168557-1168907 [Pseudomonas protegens]
MNALFIELPAFARYRKDFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFVDERRNKGRRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT

Download         Length: 351 bp

>T109172 NZ_CP031396:1168557-1168907 [Pseudomonas protegens]
ATGAATGCTCTGTTTATTGAACTACCGGCATTTGCACGATACCGAAAGGACTTCCTTGACGACGAGCTGTTCTGCGAACT
GCAGATCGAGTTGCTGCGCCACCCGCACGCAGGGGTTCTGATTCAGGGCACTGGCGGCTTGCGCAAGATGCGTTTTGTCG
ATGAGCGACGCAACAAGGGCAGGCGTGGCGGGCTGAGGGTGATCTATTACTGGTGGTCCGGAGGGGCGCAGTTCTGGCTC
TTCACCCTGTTCGACAAGGAGCAGATGGACGACCTGCTACCGCAGCAGCGACAACAGCTCAAACAACTGCTGGAACGTGA
AATCGAGGCCAGAAGACATGACCAAACGTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12086.93 Da        Isoelectric Point: 10.4439

>AT109172 WP_102864712.1 NZ_CP031396:1168894-1169211 [Pseudomonas protegens]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITATEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATP
NAQATTLMRLVERYPDTVERLASLA

Download         Length: 318 bp

>AT109172 NZ_CP031396:1168894-1169211 [Pseudomonas protegens]
ATGACCAAACGTGACATCTTTTCCGAACTGGTAGAAGGCATCGACGCCCTCACCCAGGAACGCCAGGGCAAGATCACCCT
GCGCAGCCATAAAGTGAAGCTGGACAAACTGCCCCCCATCACTGCCACCGAGGTGATGAACATCCGCCAGCAACTCAACC
TCTCGCGCTCAGTATTCGCCATGTACCTGCGGACCAACACCCGTACCCTGGAAAACTGGGAACAAGGCCGCGCCACACCC
AACGCCCAGGCCACGACCTTGATGCGCCTGGTGGAACGCTACCCGGACACAGTGGAGCGCCTCGCCTCGCTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References