108808

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 318768..319287 Replicon chromosome
Accession NZ_CP031271
Organism Staphylococcus caprae strain 26D

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DWB96_RS01330 Protein ID WP_037541722.1
Coordinates 318768..319037 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DWB96_RS01335 Protein ID WP_037541721.1
Coordinates 319030..319287 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWB96_RS13355 314854..315579 + 726 Protein_257 LPXTG cell wall anchor domain-containing protein -
DWB96_RS01310 315679..316437 + 759 WP_002444608.1 esterase family protein -
DWB96_RS01315 316519..316830 - 312 WP_002444606.1 SdpI family protein -
DWB96_RS01320 317068..318207 + 1140 WP_095323335.1 CapA family protein -
DWB96_RS01325 318258..318623 - 366 WP_037541723.1 DUF4870 domain-containing protein -
DWB96_RS01330 318768..319037 - 270 WP_037541722.1 Txe/YoeB family addiction module toxin Toxin
DWB96_RS01335 319030..319287 - 258 WP_037541721.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DWB96_RS01340 319477..320334 + 858 WP_002444596.1 ABC transporter substrate-binding protein -
DWB96_RS01345 320448..322088 - 1641 WP_002444595.1 alpha-keto acid decarboxylase family protein -
DWB96_RS01350 322260..322706 + 447 WP_002444594.1 MarR family winged helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10552.23 Da        Isoelectric Point: 10.0266

>T108808 WP_037541722.1 NZ_CP031271:c319037-318768 [Staphylococcus caprae]
MSKLNVTFTTQAFKDYQFWQQHNLGNFKKINTLLKSIARDGCIEGIGKPEALKVNYEGYYSRRITIEHRLVYKIKNDSIF
IVSCRFHYL

Download         Length: 270 bp

>T108808 NZ_CP031271:c319037-318768 [Staphylococcus caprae]
ATGAGTAAACTTAATGTGACTTTTACAACTCAAGCATTTAAAGATTATCAATTTTGGCAACAACATAACTTAGGAAATTT
TAAAAAAATTAACACTTTACTTAAAAGTATCGCACGAGATGGTTGCATCGAGGGTATCGGGAAACCGGAAGCGCTAAAAG
TCAATTATGAAGGTTATTATAGTAGGAGAATCACGATTGAACATCGGTTAGTATACAAAATAAAGAATGATTCTATTTTT
ATAGTGTCTTGTAGATTTCATTACCTATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9694.68 Da        Isoelectric Point: 4.1677

>AT108808 WP_037541721.1 NZ_CP031271:c319287-319030 [Staphylococcus caprae]
MPSINYSNARQNFKELISKVNEDSVTYTITTKEDKNAVILAEKDYNAILETMYLQSNPANVSHLNKSIQELNQNDTITVE
IDDNE

Download         Length: 258 bp

>AT108808 NZ_CP031271:c319287-319030 [Staphylococcus caprae]
ATGCCATCCATAAATTATTCCAATGCACGTCAAAATTTTAAAGAACTGATTTCTAAAGTAAACGAAGACAGTGTAACTTA
CACAATTACAACGAAAGAAGATAAGAATGCTGTCATTCTAGCTGAGAAAGATTACAATGCAATTCTAGAAACGATGTATC
TTCAGTCAAATCCGGCTAATGTGTCTCACCTGAACAAATCCATTCAAGAATTAAACCAAAACGATACGATTACAGTTGAG
ATTGATGATAATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References