Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2144019..2144281 Replicon chromosome
Accession NZ_CP031265
Organism Staphylococcus aureus strain 13

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DWB87_RS10895 Protein ID WP_001802298.1
Coordinates 2144177..2144281 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2144019..2144182 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWB87_RS10875 2140230..2140895 - 666 WP_001024095.1 SDR family oxidoreductase -
DWB87_RS10880 2141047..2141367 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DWB87_RS10885 2141369..2142349 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
DWB87_RS10890 2142615..2143706 + 1092 WP_000495683.1 hypothetical protein -
- 2144019..2144182 + 164 - - Antitoxin
DWB87_RS10895 2144177..2144281 - 105 WP_001802298.1 hypothetical protein Toxin
DWB87_RS10905 2144961..2145119 + 159 WP_001792784.1 hypothetical protein -
DWB87_RS10915 2145778..2146635 - 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
DWB87_RS10920 2146703..2147485 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T108799 WP_001802298.1 NZ_CP031265:c2144281-2144177 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T108799 NZ_CP031265:c2144281-2144177 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT108799 NZ_CP031265:2144019-2144182 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References