Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 225811..226033 Replicon chromosome
Accession NZ_CP031214
Organism Escherichia coli strain C600

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag DK885_RS01150 Protein ID WP_000141634.1
Coordinates 225926..226033 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 225811..225877 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DK885_RS01120 221252..222154 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
DK885_RS01125 222165..223148 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
DK885_RS01130 223145..224149 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
DK885_RS01135 224179..225450 - 1272 WP_001295225.1 transporter -
- 225811..225877 - 67 - - Antitoxin
DK885_RS01150 225926..226033 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
DK885_RS01155 226120..227799 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
DK885_RS01160 227796..227987 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
DK885_RS01165 227984..229555 - 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
DK885_RS01170 229828..230016 + 189 WP_001063318.1 YhjR family protein -
DK885_RS01175 230028..230780 + 753 Protein_217 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T108564 WP_000141634.1 NZ_CP031214:225926-226033 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T108564 NZ_CP031214:225926-226033 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT108564 NZ_CP031214:c225877-225811 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References