Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2187976..2188192 Replicon chromosome
Accession NZ_CP031131
Organism Staphylococcus aureus strain E16SA093

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DU470_RS11350 Protein ID WP_001802298.1
Coordinates 2188088..2188192 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2187976..2188031 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DU470_RS11330 2184179..2184844 - 666 WP_001024095.1 SDR family oxidoreductase -
DU470_RS11335 2184996..2185316 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DU470_RS11340 2185318..2186298 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
DU470_RS11345 2186564..2187655 + 1092 WP_000495681.1 hypothetical protein -
- 2187976..2188031 + 56 - - Antitoxin
DU470_RS11350 2188088..2188192 - 105 WP_001802298.1 hypothetical protein Toxin
DU470_RS14505 2188709..2188879 + 171 WP_001792292.1 transposase -
DU470_RS11360 2188872..2189030 + 159 WP_001792784.1 hypothetical protein -
DU470_RS11370 2189688..2190545 - 858 WP_000370928.1 Cof-type HAD-IIB family hydrolase -
DU470_RS11375 2190613..2191395 - 783 WP_000908189.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T108527 WP_001802298.1 NZ_CP031131:c2188192-2188088 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T108527 NZ_CP031131:c2188192-2188088 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT108527 NZ_CP031131:2187976-2188031 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References