108513

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2173340..2173556 Replicon chromosome
Accession NZ_CP031130
Organism Staphylococcus aureus strain F17SA003

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DU471_RS11300 Protein ID WP_001802298.1
Coordinates 2173452..2173556 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2173340..2173395 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DU471_RS11280 2169543..2170208 - 666 WP_001024095.1 SDR family oxidoreductase -
DU471_RS11285 2170360..2170680 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DU471_RS11290 2170682..2171662 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
DU471_RS11295 2171928..2173019 + 1092 WP_000495681.1 hypothetical protein -
- 2173340..2173395 + 56 - - Antitoxin
DU471_RS11300 2173452..2173556 - 105 WP_001802298.1 hypothetical protein Toxin
DU471_RS11310 2174236..2174394 + 159 WP_001792784.1 hypothetical protein -
DU471_RS11320 2175052..2175909 - 858 WP_000370928.1 Cof-type HAD-IIB family hydrolase -
DU471_RS11325 2175977..2176759 - 783 WP_000908189.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T108513 WP_001802298.1 NZ_CP031130:c2173556-2173452 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T108513 NZ_CP031130:c2173556-2173452 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT108513 NZ_CP031130:2173340-2173395 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References