Detailed information of TA system TA108505

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1836109..1836289
• Replicon: chromosome
• Accession: NZ_CP031130
• Organism: Staphylococcus aureus strain F17SA003

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: DU471_RS09225
• Protein ID: WP_001801861.1
• Coordinates: 1836109..1836204 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1836232..1836289 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DU471_RS09180	1831151..1831777	+	627	WP_000669021.1	hypothetical protein	-
DU471_RS09185	1831818..1832159	+	342	WP_000627547.1	DUF3969 family protein	-
DU471_RS09190	1832260..1832832	+	573	WP_000414206.1	hypothetical protein	-
DU471_RS09195	1833030..1833587	-	558	WP_000864139.1	ImmA/IrrE family metallo-endopeptidase	-
DU471_RS09205	1833958..1834134	-	177	WP_000375476.1	hypothetical protein	-
DU471_RS09210	1834145..1834528	-	384	WP_000070811.1	hypothetical protein	-
DU471_RS09215	1835213..1835659	-	447	WP_000747802.1	DUF1433 domain-containing protein	-
DU471_RS09225	1836109..1836204	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1836232..1836289	-	58	-	-	Antitoxin
DU471_RS09230	1836327..1836428	+	102	WP_001791232.1	hypothetical protein	-
DU471_RS09235	1836406..1836588	-	183	Protein_1736	transposase	-
DU471_RS09240	1836776..1837150	-	375	WP_000695818.1	DUF1433 domain-containing protein	-
DU471_RS09245	1837172..1837519	-	348	WP_001566695.1	DUF1433 domain-containing protein	-
DU471_RS09250	1837756..1838172	-	417	WP_020978241.1	DUF1433 domain-containing protein	-
DU471_RS09255	1838819..1839937	-	1119	WP_000072558.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1810294..1863440	53146

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T108505 WP_001801861.1 NZ_CP031130:1836109-1836204 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T108505 NZ_CP031130:1836109-1836204 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT108505 NZ_CP031130:c1836289-1836232 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin