Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3382535..3383130 Replicon chromosome
Accession NZ_CP031013
Organism Polaromonas sp. SP1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DT070_RS16125 Protein ID WP_122956311.1
Coordinates 3382535..3382819 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DT070_RS16130 Protein ID WP_122956312.1
Coordinates 3382816..3383130 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DT070_RS16110 3378042..3378836 + 795 WP_122956308.1 MetQ/NlpA family ABC transporter substrate-binding protein -
DT070_RS16115 3378833..3381490 - 2658 WP_194965995.1 excinuclease ABC subunit UvrA -
DT070_RS16120 3381824..3382372 + 549 WP_122956310.1 NAD(P)H-dependent oxidoreductase -
DT070_RS16125 3382535..3382819 + 285 WP_122956311.1 toxin Toxin
DT070_RS16130 3382816..3383130 + 315 WP_122956312.1 transcriptional regulator Antitoxin
DT070_RS16135 3383246..3383896 - 651 WP_122956313.1 NAD(P)H-dependent oxidoreductase -
DT070_RS16140 3384098..3385003 + 906 WP_122956314.1 LysR family transcriptional regulator -
DT070_RS16145 3385216..3385866 + 651 WP_122956315.1 peroxiredoxin -
DT070_RS16150 3385888..3386487 + 600 WP_122956316.1 alpha/beta hydrolase -
DT070_RS16155 3386484..3387497 + 1014 WP_122956317.1 sulfate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-101)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10723.26 Da        Isoelectric Point: 9.4855

>T108307 WP_122956311.1 NZ_CP031013:3382535-3382819 [Polaromonas sp. SP1]
MDDEGFRGLQEAMMRNPEAGDAIEGTGGLRKLRHGDPRRGKGKRGGLRVIYYWWDGGSQFWLFTLYDKDEMADLNAGEKK
ALKGMLKMELEAKR

Download         Length: 285 bp

>T108307 NZ_CP031013:3382535-3382819 [Polaromonas sp. SP1]
TTGGATGACGAGGGCTTTCGTGGCCTGCAAGAGGCCATGATGAGGAACCCCGAAGCCGGCGACGCGATCGAAGGTACGGG
CGGTCTGCGCAAGTTGCGGCATGGTGATCCGCGTCGAGGCAAGGGCAAACGCGGCGGCTTGCGGGTGATTTATTACTGGT
GGGATGGCGGCTCGCAATTCTGGTTGTTTACGTTGTACGACAAGGACGAAATGGCCGACCTGAACGCCGGCGAGAAGAAG
GCGCTCAAAGGAATGTTGAAAATGGAACTGGAGGCGAAGCGATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11763.45 Da        Isoelectric Point: 9.9175

>AT108307 WP_122956312.1 NZ_CP031013:3382816-3383130 [Polaromonas sp. SP1]
MKKRNLFAEITEGFDALSNARAGKQTLRTHEVEINPAPDVTADELLALRESLHLSRPVFARYLRTNPRTLENWEQGRAKP
NAQAALLIRLVEKFPDTVDRLAAV

Download         Length: 315 bp

>AT108307 NZ_CP031013:3382816-3383130 [Polaromonas sp. SP1]
ATGAAAAAGCGGAACCTGTTTGCAGAAATTACCGAGGGCTTTGACGCCCTGTCGAACGCACGGGCCGGCAAGCAGACGCT
GCGCACGCATGAAGTGGAAATAAACCCTGCGCCAGACGTGACCGCTGACGAACTGCTGGCTTTGCGCGAAAGCCTGCACC
TGTCGCGTCCGGTGTTTGCCCGCTATTTGCGAACAAACCCGCGTACGCTGGAGAACTGGGAGCAAGGGCGGGCCAAACCC
AACGCCCAGGCCGCCTTGCTGATTCGCCTGGTCGAGAAATTCCCGGACACGGTGGACCGGCTGGCCGCAGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References