Detailed information of TA system TA108242

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2675520..2675845
• Replicon: chromosome
• Accession: NZ_CP030937
• Organism: Bacillus sp. DM2

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: P54373
• Locus tag: DS740_RS14060
• Protein ID: WP_004398662.1
• Coordinates: 2675520..2675699 (+)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2675623..2675845 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DS740_RS14050	2674746..2674883	-	138	WP_021480099.1	hypothetical protein	-
DS740_RS14055	2674925..2675374	-	450	WP_032722171.1	phage portal protein	-
DS740_RS14060	2675520..2675699	+	180	WP_004398662.1	type I toxin-antitoxin system toxin TxpA	Toxin
-	2675623..2675845	-	223	NuclAT_0	-	Antitoxin
-	2675623..2675845	-	223	NuclAT_0	-	Antitoxin
-	2675623..2675845	-	223	NuclAT_0	-	Antitoxin
-	2675623..2675845	-	223	NuclAT_0	-	Antitoxin
DS740_RS14065	2676079..2676168	+	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
DS740_RS14070	2676422..2676865	-	444	WP_003229930.1	phage tail tube protein	-
DS740_RS14075	2676868..2678268	-	1401	WP_003229929.1	phage tail sheath family protein	-
DS740_RS14080	2678269..2678460	-	192	WP_010886574.1	hypothetical protein	-
DS740_RS14085	2678457..2678894	-	438	WP_003229927.1	hypothetical protein	-
DS740_RS14090	2678907..2679410	-	504	WP_003246050.1	HK97 gp10 family phage protein	-
DS740_RS14095	2679407..2679769	-	363	WP_003229925.1	YqbH/XkdH family protein	-
DS740_RS14100	2679766..2680161	-	396	WP_004398566.1	DUF3199 family protein	-
DS740_RS14105	2680165..2680476	-	312	WP_003229923.1	YqbF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2645053..2696523	51470

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T108242 WP_004398662.1 NZ_CP030937:2675520-2675699 [Bacillus sp. DM2]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T108242 NZ_CP030937:2675520-2675699 [Bacillus sp. DM2]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin

Nucleotide

• Length: 223 bp

>AT108242 NZ_CP030937:c2675845-2675623 [Bacillus sp. DM2]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Toxin

• AlphaFold DB: A0A164X333

Antitoxin