Detailed information of TA system TA108228

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2231127..2231456
• Replicon: chromosome
• Accession: NZ_CP030937
• Organism: Bacillus sp. DM2

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: DS740_RS11515
• Protein ID: WP_109962751.1
• Coordinates: 2231127..2231378 (-)
• Length: 84 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2231356..2231456 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DS740_RS11465	2226170..2226397	-	228	WP_041338771.1	helix-turn-helix transcriptional regulator	-
DS740_RS11470	2226490..2226927	-	438	WP_114168600.1	hypothetical protein	-
DS740_RS11475	2227018..2227401	-	384	WP_114168681.1	UPF0715 family protein	-
DS740_RS11480	2227481..2227816	-	336	WP_114168602.1	hypothetical protein	-
DS740_RS11485	2227854..2228150	-	297	WP_114168604.1	hypothetical protein	-
DS740_RS11490	2228226..2228471	-	246	WP_114168606.1	hypothetical protein	-
DS740_RS11495	2228670..2228951	-	282	WP_050496376.1	hypothetical protein	-
DS740_RS11500	2228985..2229239	-	255	WP_100244913.1	hypothetical protein	-
DS740_RS11505	2229595..2230812	-	1218	WP_114168608.1	hypothetical protein	-
DS740_RS11510	2230894..2231082	-	189	WP_114168610.1	hypothetical protein	-
DS740_RS11515	2231127..2231378	-	252	WP_109962751.1	hypothetical protein	Toxin
-	2231356..2231456	+	101	-	-	Antitoxin
DS740_RS11520	2231397..2231573	-	177	WP_109962752.1	hypothetical protein	-
-	2231514..2231614	+	101	NuclAT_1	-	-
-	2231514..2231614	+	101	NuclAT_1	-	-
-	2231514..2231614	+	101	NuclAT_1	-	-
-	2231514..2231614	+	101	NuclAT_1	-	-
DS740_RS11525	2232528..2232722	+	195	WP_003230986.1	hypothetical protein	-
DS740_RS11530	2232762..2235281	+	2520	WP_019712270.1	hypothetical protein	-
DS740_RS11535	2235525..2235803	+	279	WP_004399274.1	HU-related DNA-binding protein HupN	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2163700..2286801	123101

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 10072.08 Da
• Isoelectric Point: 10.0301

>T108228 WP_109962751.1 NZ_CP030937:c2231378-2231127 [Bacillus sp. DM2]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSNEAQTLINTIFVVTCIIAILLWIIYFVFLKLRN
KSH

Nucleotide

• Length: 252 bp

>T108228 NZ_CP030937:c2231378-2231127 [Bacillus sp. DM2]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACTCATATCACTTTCATTGGCTTATTCTTAATGTTTCAACTCATTAAGGATTACTTCAGCAACGAAGCACAAACACTAA
TCAATACAATTTTTGTAGTCACGTGTATCATTGCCATATTGTTGTGGATCATCTATTTTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin

Nucleotide

• Length: 101 bp

>AT108228 NZ_CP030937:2231356-2231456 [Bacillus sp. DM2]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATATGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Antitoxin