Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 591..1132 Replicon plasmid unnamed2
Accession NZ_CP030873
Organism Acetobacter sp. JWB

Toxin (Protein)


Gene name yoeB Uniprot ID A0A252ELZ7
Locus tag DS739_RS13985 Protein ID WP_039891754.1
Coordinates 591..860 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID F1YTL2
Locus tag DS739_RS13990 Protein ID WP_006116374.1
Coordinates 857..1132 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DS739_RS13980 182..409 - 228 WP_039891752.1 AbrB family transcriptional regulator -
DS739_RS13985 591..860 - 270 WP_039891754.1 Txe/YoeB family addiction module toxin Toxin
DS739_RS13990 857..1132 - 276 WP_006116374.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DS739_RS14240 1958..2131 + 174 WP_157884551.1 hypothetical protein -
DS739_RS13995 2480..2854 + 375 WP_139018868.1 hypothetical protein -
DS739_RS14000 2868..3200 + 333 WP_081461445.1 hypothetical protein -
DS739_RS14005 3256..3660 - 405 WP_006116376.1 DUF2442 domain-containing protein -
DS739_RS14010 3973..4395 - 423 WP_039891761.1 type II toxin-antitoxin system VapC family toxin -
DS739_RS14015 4392..4637 - 246 WP_170315311.1 plasmid stabilization protein -
DS739_RS14020 4748..5002 - 255 WP_081461446.1 hypothetical protein -
DS739_RS14025 5087..5329 - 243 WP_170315312.1 BrnA antitoxin family protein -
DS739_RS14030 5340..5516 - 177 Protein_12 BrnT family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..17910 17910


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10660.00 Da        Isoelectric Point: 6.9785

>T108119 WP_039891754.1 NZ_CP030873:c860-591 [Acetobacter sp. JWB]
VTVVFHEDGWEDYLSWFRSDHAVLEKINALIEDVRRHPFQGLGKPEPLKGQLSGWWSRRITGEHRLVYRVQGRVEEDQRI
EVAQCRFHY

Download         Length: 270 bp

>T108119 NZ_CP030873:c860-591 [Acetobacter sp. JWB]
GTGACAGTCGTTTTTCATGAAGATGGCTGGGAGGATTATCTTTCGTGGTTCCGCTCAGACCATGCGGTTCTTGAGAAGAT
CAATGCCCTGATTGAGGATGTAAGGCGGCATCCGTTTCAGGGGCTGGGCAAGCCGGAACCGCTGAAAGGTCAGCTTTCCG
GGTGGTGGTCTCGTCGGATTACGGGAGAACATCGTCTGGTCTACCGGGTTCAGGGGCGTGTGGAGGAGGATCAGCGGATT
GAGGTCGCACAGTGTCGGTTTCATTACTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10224.36 Da        Isoelectric Point: 4.8562

>AT108119 WP_006116374.1 NZ_CP030873:c1132-857 [Acetobacter sp. JWB]
MTCVSYTDLRQNLAHYLDEAVNSRAPIVVTRKTGKGSVVLMSEEEFSGWQETVHLLSSPRNAERLLRSIRDIEHGTATEH
DLLEPQGESSE

Download         Length: 276 bp

>AT108119 NZ_CP030873:c1132-857 [Acetobacter sp. JWB]
ATGACCTGTGTTTCCTATACCGACTTGCGCCAGAACCTGGCGCATTATCTGGACGAAGCCGTGAACAGCCGCGCGCCGAT
TGTCGTGACCCGCAAGACCGGGAAAGGCAGTGTCGTGCTGATGTCGGAAGAAGAATTCTCCGGCTGGCAGGAGACCGTGC
ATCTCCTGAGCAGCCCGCGCAACGCGGAGAGGCTGTTGCGGAGTATCCGAGACATTGAGCACGGGACCGCGACCGAGCAT
GATCTTCTGGAGCCGCAGGGTGAATCGTCAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A252ELZ7

Antitoxin

Source ID Structure
AlphaFold DB A0A252ELY2

References