Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 702807..703065 Replicon chromosome
Accession NZ_CP030787
Organism Escherichia albertii strain 2013C-4143

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag CX698_RS03360 Protein ID WP_000809168.1
Coordinates 702807..702959 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 703008..703065 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CX698_RS03335 698045..698758 - 714 WP_001102344.1 acidic protein MsyB -
CX698_RS03340 698785..699189 - 405 WP_000833521.1 DUF2541 family protein -
CX698_RS03350 699564..701480 + 1917 WP_113639976.1 molecular chaperone DnaK -
CX698_RS03355 701569..702699 + 1131 WP_001118445.1 molecular chaperone DnaJ -
CX698_RS03360 702807..702959 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 703008..703065 + 58 - - Antitoxin
CX698_RS03365 703582..704343 + 762 WP_001276206.1 membrane protein -
CX698_RS03370 704364..705857 + 1494 WP_113639977.1 sulfatase-like hydrolase/transferase -
CX698_RS03375 706011..707258 + 1248 WP_059214856.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T108046 WP_000809168.1 NZ_CP030787:c702959-702807 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T108046 NZ_CP030787:c702959-702807 [Escherichia albertii]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT108046 NZ_CP030787:703008-703065 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References