Detailed information of TA system TA108043

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symE-OrzO/SymE(toxin)
• Location: 626324..626736
• Replicon: chromosome
• Accession: NZ_CP030787
• Organism: Escherichia albertii strain 2013C-4143

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: CX698_RS02985
• Protein ID: WP_000132637.1
• Coordinates: 626324..626665 (-)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	OrzO
Locus tag	-
Coordinates	626660..626736 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CX698_RS02965	621924..622856	+	933	WP_113639964.1	Rpn family recombination-promoting nuclease/putative transposase	-
CX698_RS23680	623009..623182	-	174	Protein_552	GntR family transcriptional regulator	-
CX698_RS02970	623236..623930	+	695	WP_085949012.1	IS1 family transposase	-
CX698_RS23685	624181..626277	+	2097	WP_000648210.1	DUF262 domain-containing protein	-
CX698_RS02985	626324..626665	-	342	WP_000132637.1	endoribonuclease SymE	Toxin
-	626660..626736	+	77	NuclAT_5	-	Antitoxin
-	626660..626736	+	77	NuclAT_5	-	Antitoxin
-	626660..626736	+	77	NuclAT_5	-	Antitoxin
-	626660..626736	+	77	NuclAT_5	-	Antitoxin
-	626660..626736	+	77	NuclAT_6	-	Antitoxin
-	626660..626736	+	77	NuclAT_6	-	Antitoxin
-	626660..626736	+	77	NuclAT_6	-	Antitoxin
-	626660..626736	+	77	NuclAT_6	-	Antitoxin
CX698_RS02990	626894..628249	-	1356	WP_001272444.1	restriction endonuclease subunit S	-
CX698_RS02995	628246..629835	-	1590	WP_001063210.1	type I restriction-modification system methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12368.20 Da
• Isoelectric Point: 7.8219

>T108043 WP_000132637.1 NZ_CP030787:c626665-626324 [Escherichia albertii]
MTDTHSIAQPFEAEVTPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVQEFIGVITGKQKVA

Nucleotide

• Length: 342 bp

>T108043 NZ_CP030787:c626665-626324 [Escherichia albertii]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCACCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCCCCCGCCGCCGAAGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAAGCAGGTGCAGGAGTTTATTGGGGTAATTAC
AGGTAAACAGAAAGTCGCCTGA

Antitoxin

Nucleotide

• Length: 77 bp

>AT108043 NZ_CP030787:626660-626736 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin