Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4735762..4736020 Replicon chromosome
Accession NZ_CP030781
Organism Escherichia albertii strain 07-3866

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag CCF18_RS23515 Protein ID WP_000809168.1
Coordinates 4735762..4735914 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4735963..4736020 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCF18_RS23495 4731004..4731717 - 714 WP_001102345.1 acidic protein MsyB -
CCF18_RS23500 4731744..4732148 - 405 WP_000833521.1 DUF2541 family protein -
CCF18_RS23505 4732523..4734439 + 1917 WP_000516135.1 molecular chaperone DnaK -
CCF18_RS23510 4734528..4735658 + 1131 WP_001118445.1 molecular chaperone DnaJ -
CCF18_RS23515 4735762..4735914 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 4735963..4736020 + 58 - - Antitoxin
CCF18_RS23520 4736537..4737298 + 762 WP_059273362.1 hypothetical protein -
CCF18_RS23525 4737319..4738812 + 1494 WP_059216552.1 sulfatase-like hydrolase/transferase -
CCF18_RS23530 4738966..4740213 + 1248 WP_105210836.1 cytoplasmic protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T108002 WP_000809168.1 NZ_CP030781:c4735914-4735762 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T108002 NZ_CP030781:c4735914-4735762 [Escherichia albertii]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTCTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT108002 NZ_CP030781:4735963-4736020 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References