Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 128939..129444 Replicon chromosome
Accession NZ_CP030781
Organism Escherichia albertii strain 07-3866

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CCF18_RS00715 Protein ID WP_125317184.1
Coordinates 129184..129444 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CCF18_RS00710 Protein ID WP_125317183.1
Coordinates 128939..129184 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCF18_RS00690 124182..124436 + 255 WP_125317179.1 Derepression protein -
CCF18_RS00695 124500..127232 + 2733 WP_125317180.1 TOPRIM and DUF927 domain-containing protein -
CCF18_RS00700 127617..128147 + 531 WP_125317181.1 hypothetical protein -
CCF18_RS00705 128189..128446 - 258 WP_125317182.1 ogr/Delta-like zinc finger family protein -
CCF18_RS00710 128939..129184 + 246 WP_125317183.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CCF18_RS00715 129184..129444 + 261 WP_125317184.1 Txe/YoeB family addiction module toxin Toxin
CCF18_RS00725 129839..130852 - 1014 WP_000061297.1 sulfite reductase subunit C -
CCF18_RS00730 130863..131681 - 819 WP_054412607.1 anaerobic sulfite reductase subunit AsrB -
CCF18_RS00735 131685..132728 - 1044 WP_125317185.1 anaerobic sulfite reductase subunit AsrA -
CCF18_RS00740 133094..133747 + 654 WP_077871365.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10167.82 Da        Isoelectric Point: 10.2570

>T107979 WP_125317184.1 NZ_CP030781:129184-129444 [Escherichia albertii]
MKVRISPQAKGDLQYWAENDPKTHNKVIELIKSAKESPFKGIGKPEALKHRKPLWSRRITKEHRLVYYVEQGDLYIVACR
YHYTTI

Download         Length: 261 bp

>T107979 NZ_CP030781:129184-129444 [Escherichia albertii]
ATGAAAGTCAGGATATCCCCGCAGGCAAAAGGCGATCTTCAGTACTGGGCTGAGAATGACCCAAAGACGCATAACAAGGT
AATAGAGCTAATCAAATCGGCTAAGGAAAGCCCCTTCAAGGGGATAGGGAAGCCGGAGGCGCTAAAGCACCGTAAGCCCC
TCTGGTCACGCCGAATCACGAAAGAACATCGTCTGGTGTATTACGTTGAGCAAGGCGATCTGTACATTGTTGCGTGTCGT
TATCACTACACCACGATTTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9050.08 Da        Isoelectric Point: 4.4180

>AT107979 WP_125317183.1 NZ_CP030781:128939-129184 [Escherichia albertii]
MQHINYTDARQHLADLMQQANDDRAPILVTRKGAKSVVMIDAEEFASIQETLHLFSNPANAAHIEASLASLERGDYEELD
I

Download         Length: 246 bp

>AT107979 NZ_CP030781:128939-129184 [Escherichia albertii]
ATGCAACACATTAACTACACCGATGCTCGACAGCATTTAGCTGACCTGATGCAGCAGGCTAATGATGATCGTGCGCCAAT
CCTGGTTACGCGTAAGGGGGCTAAAAGCGTGGTAATGATCGACGCGGAGGAGTTCGCATCGATTCAGGAAACGTTGCACC
TGTTCAGTAACCCGGCGAACGCTGCACACATTGAAGCCAGCCTTGCATCGCTCGAACGCGGCGATTATGAGGAACTGGAC
ATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References