Detailed information of TA system TA107955

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symER/SymE(toxin)
• Location: 2236548..2236960
• Replicon: chromosome
• Accession: NZ_CP030778
• Organism: Escherichia albertii strain 05-3106

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: CYM74_RS11115
• Protein ID: WP_044708303.1
• Coordinates: 2236619..2236960 (+)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	symR
Locus tag	-
Coordinates	2236548..2236624 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CYM74_RS11105	2231646..2233046	+	1401	WP_059254411.1	restriction endonuclease subunit S	-
CYM74_RS11110	2233141..2236404	+	3264	WP_059254413.1	type I restriction endonuclease subunit R	-
-	2236548..2236624	-	77	NuclAT_10	-	Antitoxin
-	2236548..2236624	-	77	NuclAT_10	-	Antitoxin
-	2236548..2236624	-	77	NuclAT_10	-	Antitoxin
-	2236548..2236624	-	77	NuclAT_10	-	Antitoxin
-	2236548..2236624	-	77	NuclAT_9	-	Antitoxin
-	2236548..2236624	-	77	NuclAT_9	-	Antitoxin
-	2236548..2236624	-	77	NuclAT_9	-	Antitoxin
-	2236548..2236624	-	77	NuclAT_9	-	Antitoxin
CYM74_RS11115	2236619..2236960	+	342	WP_044708303.1	endoribonuclease SymE	Toxin
CYM74_RS11120	2237007..2237864	-	858	Protein_2146	DUF1524 domain-containing protein	-
CYM74_RS11125	2238051..2238983	-	933	WP_113622969.1	Rpn family recombination-promoting nuclease/putative transposase	-
CYM74_RS11130	2239170..2240450	+	1281	WP_059238725.1	DUF445 domain-containing protein	-
CYM74_RS11135	2240570..2241721	+	1152	WP_054409953.1	2-hydroxyacyl-CoA dehydratase subunit D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12384.20 Da
• Isoelectric Point: 7.8219

>T107955 WP_044708303.1 NZ_CP030778:2236619-2236960 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPTITLKGQWLEAAGFATGTVVDVKVMEGCIVLTTQPPAAEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

>T107955 NZ_CP030778:2236619-2236960 [Escherichia albertii]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCACCATTACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTTACCACCCAACCACCCGCCGCCGAAGAGAGCGAA
CTGATGCAGTCGCTACGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAGAAGCAGGTGCAGGAGTTTATTGGGGTGATTGC
CGGTAAACAGAAAGTCGCCTGA

Antitoxin

Nucleotide

• Length: 77 bp

>AT107955 NZ_CP030778:c2236624-2236548 [Escherichia albertii]
AGTCATGATTACTATTCTCCATAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin