Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 2158188..2158446 Replicon chromosome
Accession NZ_CP030778
Organism Escherichia albertii strain 05-3106

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag CYM74_RS10730 Protein ID WP_000809168.1
Coordinates 2158294..2158446 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 2158188..2158245 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYM74_RS10715 2153990..2155238 - 1249 Protein_2068 cytoplasmic protein -
CYM74_RS10720 2155392..2156889 - 1498 Protein_2069 sulfatase-like hydrolase/transferase -
CYM74_RS10725 2156910..2157671 - 762 WP_059216553.1 hypothetical protein -
- 2158188..2158245 - 58 - - Antitoxin
CYM74_RS10730 2158294..2158446 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
CYM74_RS10735 2158640..2159752 - 1113 WP_024179954.1 IS4-like element IS421 family transposase -
CYM74_RS10740 2159899..2161029 - 1131 WP_001118445.1 molecular chaperone DnaJ -
CYM74_RS10745 2161118..2163034 - 1917 WP_000516135.1 molecular chaperone DnaK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T107952 WP_000809168.1 NZ_CP030778:2158294-2158446 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T107952 NZ_CP030778:2158294-2158446 [Escherichia albertii]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTCTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT107952 NZ_CP030778:c2158245-2158188 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References