Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2224..2809 Replicon plasmid unnamed3
Accession NZ_CP030757
Organism Acinetobacter schindleri strain H3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DPR03_RS15705 Protein ID WP_145758468.1
Coordinates 2489..2809 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DPR03_RS15700 Protein ID WP_004896911.1
Coordinates 2224..2496 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DPR03_RS15680 365..889 + 525 WP_145758466.1 plasmid replication DNA-binding protein -
DPR03_RS15685 1205..1486 + 282 WP_145758467.1 hypothetical protein -
DPR03_RS15690 1551..1774 + 224 Protein_3 DUF2798 domain-containing protein -
DPR03_RS15700 2224..2496 - 273 WP_004896911.1 helix-turn-helix domain-containing protein Antitoxin
DPR03_RS15705 2489..2809 - 321 WP_145758468.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DPR03_RS15710 2949..3626 - 678 WP_143045205.1 RloB domain-containing protein -
DPR03_RS15715 3641..4930 - 1290 WP_071321328.1 ATP-binding protein -
DPR03_RS15720 5158..5487 - 330 WP_071321327.1 hypothetical protein -
DPR03_RS15725 5714..7063 - 1350 WP_071321326.1 MobA/MobL family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..29258 29258


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(41-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-85)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12255.10 Da        Isoelectric Point: 7.9835

>T107844 WP_145758468.1 NZ_CP030757:c2809-2489 [Acinetobacter schindleri]
MLFIETSIFTKQIKELLSDEEYRQLQQDLLVQPDKGDLIKNGGGIRKVRCAQGNKGKSGGIRVIYYWVTEDDQIFFLVAY
PKSMKDNLTDKETSILRQLVKEQFHG

Download         Length: 321 bp

>T107844 NZ_CP030757:c2809-2489 [Acinetobacter schindleri]
ATGTTATTCATTGAAACCAGTATTTTTACCAAGCAAATCAAAGAGCTTTTGAGTGATGAAGAGTATCGTCAGCTTCAGCA
AGATCTCTTGGTACAGCCTGATAAGGGCGACTTAATCAAGAATGGCGGTGGAATTCGTAAAGTACGTTGTGCTCAGGGCA
ATAAAGGTAAAAGTGGCGGTATCCGTGTGATCTATTACTGGGTCACAGAAGATGATCAGATATTTTTCCTGGTGGCTTAT
CCAAAGTCTATGAAAGATAATCTGACAGACAAAGAGACCTCTATTTTGCGTCAATTAGTGAAGGAGCAATTTCATGGATA
A

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10126.59 Da        Isoelectric Point: 7.2045

>AT107844 WP_004896911.1 NZ_CP030757:c2496-2224 [Acinetobacter schindleri]
MDNNLFDDLVASIKEAGAIKRNEMKASRVTELELPDIKEVREKTGLTQAEFAARLHISARTLQNWEQGRRYPTGPAATLI
RILDAHPTLI

Download         Length: 273 bp

>AT107844 NZ_CP030757:c2496-2224 [Acinetobacter schindleri]
ATGGATAACAACTTATTTGATGACCTGGTTGCTTCAATCAAAGAAGCTGGTGCCATCAAACGCAATGAAATGAAAGCAAG
CCGGGTAACTGAGCTTGAATTGCCGGATATTAAGGAAGTACGTGAGAAGACAGGCTTAACCCAAGCTGAATTTGCTGCAC
GTTTGCATATCAGTGCCAGAACCCTGCAAAACTGGGAACAAGGCCGTCGCTATCCGACTGGTCCTGCAGCGACGCTAATT
CGTATTCTGGATGCCCATCCAACTCTGATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References