Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1115509..1115772 Replicon chromosome
Accession NZ_CP030323
Organism Staphylococcus aureus strain AR_475

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CSC60_RS05520 Protein ID WP_001802298.1
Coordinates 1115509..1115613 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 1115608..1115772 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC60_RS05495 1110903..1111685 + 783 WP_000908190.1 ABC transporter ATP-binding protein -
CSC60_RS05500 1111753..1112610 + 858 WP_031844942.1 Cof-type HAD-IIB family hydrolase -
CSC60_RS05505 1113305..1113397 - 93 WP_031844941.1 hypothetical protein -
CSC60_RS05510 1113686..1114822 + 1137 Protein_1040 SAP domain-containing protein -
CSC60_RS14430 1114865..1115348 + 484 Protein_1041 recombinase family protein -
CSC60_RS05520 1115509..1115613 + 105 WP_001802298.1 hypothetical protein Toxin
- 1115608..1115772 - 165 - - Antitoxin
CSC60_RS05525 1116062..1117153 - 1092 WP_000495695.1 hypothetical protein -
CSC60_RS05530 1117419..1118396 - 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
CSC60_RS05535 1118398..1118718 - 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSC60_RS05540 1118870..1119535 + 666 WP_001024088.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T107674 WP_001802298.1 NZ_CP030323:1115509-1115613 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T107674 NZ_CP030323:1115509-1115613 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT107674 NZ_CP030323:c1115772-1115608 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References