Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 828768..828952 Replicon chromosome
Accession NZ_CP030323
Organism Staphylococcus aureus strain AR_475

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CSC60_RS03990 Protein ID WP_000482647.1
Coordinates 828768..828875 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 828892..828952 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC60_RS03965 824130..824603 + 474 WP_000456483.1 GyrI-like domain-containing protein -
CSC60_RS03970 824726..825937 - 1212 WP_001191921.1 multidrug effflux MFS transporter -
CSC60_RS03975 826120..826779 - 660 WP_000831298.1 membrane protein -
CSC60_RS03980 826839..827981 - 1143 WP_001176863.1 glycerate kinase -
CSC60_RS03985 828249..828635 + 387 WP_000779353.1 flippase GtxA -
CSC60_RS03990 828768..828875 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 828892..828952 - 61 - - Antitoxin
CSC60_RS14420 828902..829069 + 168 WP_000301893.1 hypothetical protein -
CSC60_RS03995 829523..831286 + 1764 WP_001064822.1 ABC transporter ATP-binding protein/permease -
CSC60_RS04000 831311..833044 + 1734 WP_000488493.1 ABC transporter ATP-binding protein/permease -
CSC60_RS04010 833275..833442 + 168 WP_031845053.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T107671 WP_000482647.1 NZ_CP030323:828768-828875 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T107671 NZ_CP030323:828768-828875 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT107671 NZ_CP030323:c828952-828892 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References