Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 5343026..5343597 Replicon chromosome
Accession NZ_CP030265
Organism Skermanella pratensis strain W17

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DPR14_RS24565 Protein ID WP_158047493.1
Coordinates 5343328..5343597 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DPR14_RS24560 Protein ID WP_158047492.1
Coordinates 5343026..5343331 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DPR14_RS24545 5340311..5340643 - 333 WP_158047489.1 sarcosine oxidase subunit delta -
DPR14_RS24550 5340661..5341914 - 1254 WP_158047490.1 sarcosine oxidase subunit beta family protein -
DPR14_RS24555 5342039..5342947 + 909 WP_158047491.1 EamA family transporter -
DPR14_RS24560 5343026..5343331 + 306 WP_158047492.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DPR14_RS24565 5343328..5343597 + 270 WP_158047493.1 Txe/YoeB family addiction module toxin Toxin
DPR14_RS24570 5343692..5344069 - 378 WP_158047494.1 hypothetical protein -
DPR14_RS24575 5344056..5344352 - 297 WP_158047495.1 hypothetical protein -
DPR14_RS24580 5344672..5346195 - 1524 WP_158043490.1 group II intron reverse transcriptase/maturase -
DPR14_RS24590 5346614..5347690 - 1077 WP_158047496.1 GlxA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10694.08 Da        Isoelectric Point: 9.5445

>T107425 WP_158047493.1 NZ_CP030265:5343328-5343597 [Skermanella pratensis]
MTRLAWTDAAWEDYTWWQDNDRKTARRINELIKSALRTPFDGLGKPEPLKGDWAGWWSRRITLEHRLVYRISRNGGDETL
IIAQCRYHY

Download         Length: 270 bp

>T107425 NZ_CP030265:5343328-5343597 [Skermanella pratensis]
TTGACGAGGCTTGCCTGGACCGATGCTGCCTGGGAAGACTACACATGGTGGCAGGATAACGATCGCAAGACCGCCCGCAG
GATCAACGAACTGATCAAGAGCGCCCTGCGAACACCTTTCGACGGGCTTGGGAAGCCTGAACCCTTGAAAGGTGACTGGG
CGGGCTGGTGGTCTCGGCGGATAACCTTGGAACACCGTCTGGTTTATCGGATATCCAGGAACGGCGGCGACGAGACATTG
ATCATCGCTCAATGCCGTTATCACTACTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11317.59 Da        Isoelectric Point: 4.7078

>AT107425 WP_158047492.1 NZ_CP030265:5343026-5343331 [Skermanella pratensis]
MGHVSYSELRQNLARYMDEVCDSNAPLVVTRQNARSVVMISQDEYESMAATLHLMKSPRNALRLIQSMEDAKAGRVSERG
LIEGHDDEAGVLHRTDDGEQD

Download         Length: 306 bp

>AT107425 NZ_CP030265:5343026-5343331 [Skermanella pratensis]
ATGGGGCACGTCAGCTATTCTGAATTGCGGCAAAATCTCGCTCGCTATATGGACGAGGTGTGCGATAGCAACGCGCCTCT
CGTCGTCACTCGGCAGAACGCACGCTCTGTCGTGATGATAAGCCAGGATGAATATGAGAGCATGGCCGCAACTCTCCACC
TCATGAAATCACCTCGAAACGCCCTGCGGCTGATCCAGTCCATGGAAGATGCGAAGGCTGGCCGCGTGAGTGAAAGAGGA
TTGATAGAGGGGCACGACGACGAGGCGGGGGTCCTCCATCGCACGGATGACGGTGAGCAGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References