Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 100312..100867 Replicon chromosome
Accession NZ_CP030241
Organism Moraxella bovis strain Epp63 (300)

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DQF64_RS00475 Protein ID WP_078274755.1
Coordinates 100583..100867 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DQF64_RS00470 Protein ID WP_078274722.1
Coordinates 100312..100593 (-) Length 94 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQF64_RS00445 96010..96768 + 759 WP_078274726.1 YciK family oxidoreductase -
DQF64_RS00450 96878..98203 + 1326 WP_112741690.1 hemolysin family protein -
DQF64_RS00455 98348..99070 + 723 WP_029103568.1 nitroreductase family protein -
DQF64_RS00460 99110..99322 - 213 WP_078274724.1 hypothetical protein -
DQF64_RS00465 99438..100262 - 825 WP_078274723.1 site-specific integrase -
DQF64_RS00470 100312..100593 - 282 WP_078274722.1 helix-turn-helix domain-containing protein Antitoxin
DQF64_RS00475 100583..100867 - 285 WP_078274755.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQF64_RS00480 100982..102142 - 1161 WP_078274721.1 hypothetical protein -
DQF64_RS00485 102228..102521 - 294 WP_078274720.1 DUF2523 domain-containing protein -
DQF64_RS14795 102518..103393 - 876 WP_162860331.1 hypothetical protein -
DQF64_RS00500 103886..104143 - 258 WP_112741693.1 hypothetical protein -
DQF64_RS00505 104214..104591 + 378 WP_112741694.1 hypothetical protein -
DQF64_RS00510 104714..104959 + 246 WP_078274709.1 hypothetical protein -
DQF64_RS00515 105246..105521 + 276 WP_078274708.1 hypothetical protein -
DQF64_RS14800 105516..105671 - 156 WP_158079680.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(26-89)

Antitoxin

(36-84)


Sequences


Toxin        


Download         Length: 95 a.a.        Molecular weight: 10647.33 Da        Isoelectric Point: 10.2808

>T107402 WP_078274755.1 NZ_CP030241:c100867-100583 [Moraxella bovis]
MDDDEYRLLQTNLMKNPHQGDIVRGTGGVRKTRWSIDGKGKSGGSRIIYFFVDGAGIFFMLLAYPKSKQTTLSADEKKEM
LKLTTAIKEIYRAK

Download         Length: 285 bp

>T107402 NZ_CP030241:c100867-100583 [Moraxella bovis]
ATGGATGATGACGAGTACAGACTATTACAAACAAACTTGATGAAAAACCCACATCAAGGCGACATTGTTCGTGGTACTGG
CGGAGTACGCAAAACAAGATGGTCAATTGATGGCAAGGGCAAAAGTGGTGGCAGTCGCATCATTTACTTTTTTGTTGATG
GTGCTGGCATTTTCTTTATGCTCTTGGCTTATCCTAAATCAAAACAAACAACGCTATCGGCGGATGAGAAAAAAGAAATG
CTCAAACTAACCACCGCAATTAAGGAGATTTACCGTGCAAAATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10425.98 Da        Isoelectric Point: 10.0023

>AT107402 WP_078274722.1 NZ_CP030241:c100593-100312 [Moraxella bovis]
VQNEFYDDLKASLTEALAIAKGEISPSRTFTYERPNIKDIRAKTGLSQTQFAQKLHISPKTLKNWEQGIRTPTGPAITLI
RLLDKNPDLISMA

Download         Length: 282 bp

>AT107402 NZ_CP030241:c100593-100312 [Moraxella bovis]
GTGCAAAATGAGTTTTACGATGATTTAAAAGCCTCATTGACTGAGGCTCTGGCAATCGCTAAGGGCGAAATTTCCCCAAG
TCGTACATTCACTTATGAACGCCCAAACATCAAAGATATTCGGGCAAAAACAGGGCTATCACAAACCCAGTTCGCCCAGA
AGCTACACATAAGCCCTAAAACGCTTAAAAACTGGGAACAGGGCATTAGAACGCCAACAGGTCCAGCCATTACCCTAATT
AGATTACTTGACAAAAACCCTGATTTAATTAGCATGGCATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References