Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/RelE-HTH |
Location | 100312..100867 | Replicon | chromosome |
Accession | NZ_CP030241 | ||
Organism | Moraxella bovis strain Epp63 (300) |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | DQF64_RS00475 | Protein ID | WP_078274755.1 |
Coordinates | 100583..100867 (-) | Length | 95 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | DQF64_RS00470 | Protein ID | WP_078274722.1 |
Coordinates | 100312..100593 (-) | Length | 94 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DQF64_RS00445 | 96010..96768 | + | 759 | WP_078274726.1 | YciK family oxidoreductase | - |
DQF64_RS00450 | 96878..98203 | + | 1326 | WP_112741690.1 | hemolysin family protein | - |
DQF64_RS00455 | 98348..99070 | + | 723 | WP_029103568.1 | nitroreductase family protein | - |
DQF64_RS00460 | 99110..99322 | - | 213 | WP_078274724.1 | hypothetical protein | - |
DQF64_RS00465 | 99438..100262 | - | 825 | WP_078274723.1 | site-specific integrase | - |
DQF64_RS00470 | 100312..100593 | - | 282 | WP_078274722.1 | helix-turn-helix domain-containing protein | Antitoxin |
DQF64_RS00475 | 100583..100867 | - | 285 | WP_078274755.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
DQF64_RS00480 | 100982..102142 | - | 1161 | WP_078274721.1 | hypothetical protein | - |
DQF64_RS00485 | 102228..102521 | - | 294 | WP_078274720.1 | DUF2523 domain-containing protein | - |
DQF64_RS14795 | 102518..103393 | - | 876 | WP_162860331.1 | hypothetical protein | - |
DQF64_RS00500 | 103886..104143 | - | 258 | WP_112741693.1 | hypothetical protein | - |
DQF64_RS00505 | 104214..104591 | + | 378 | WP_112741694.1 | hypothetical protein | - |
DQF64_RS00510 | 104714..104959 | + | 246 | WP_078274709.1 | hypothetical protein | - |
DQF64_RS00515 | 105246..105521 | + | 276 | WP_078274708.1 | hypothetical protein | - |
DQF64_RS14800 | 105516..105671 | - | 156 | WP_158079680.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 95 a.a. Molecular weight: 10647.33 Da Isoelectric Point: 10.2808
>T107402 WP_078274755.1 NZ_CP030241:c100867-100583 [Moraxella bovis]
MDDDEYRLLQTNLMKNPHQGDIVRGTGGVRKTRWSIDGKGKSGGSRIIYFFVDGAGIFFMLLAYPKSKQTTLSADEKKEM
LKLTTAIKEIYRAK
MDDDEYRLLQTNLMKNPHQGDIVRGTGGVRKTRWSIDGKGKSGGSRIIYFFVDGAGIFFMLLAYPKSKQTTLSADEKKEM
LKLTTAIKEIYRAK
Download Length: 285 bp
>T107402 NZ_CP030241:c100867-100583 [Moraxella bovis]
ATGGATGATGACGAGTACAGACTATTACAAACAAACTTGATGAAAAACCCACATCAAGGCGACATTGTTCGTGGTACTGG
CGGAGTACGCAAAACAAGATGGTCAATTGATGGCAAGGGCAAAAGTGGTGGCAGTCGCATCATTTACTTTTTTGTTGATG
GTGCTGGCATTTTCTTTATGCTCTTGGCTTATCCTAAATCAAAACAAACAACGCTATCGGCGGATGAGAAAAAAGAAATG
CTCAAACTAACCACCGCAATTAAGGAGATTTACCGTGCAAAATGA
ATGGATGATGACGAGTACAGACTATTACAAACAAACTTGATGAAAAACCCACATCAAGGCGACATTGTTCGTGGTACTGG
CGGAGTACGCAAAACAAGATGGTCAATTGATGGCAAGGGCAAAAGTGGTGGCAGTCGCATCATTTACTTTTTTGTTGATG
GTGCTGGCATTTTCTTTATGCTCTTGGCTTATCCTAAATCAAAACAAACAACGCTATCGGCGGATGAGAAAAAAGAAATG
CTCAAACTAACCACCGCAATTAAGGAGATTTACCGTGCAAAATGA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10425.98 Da Isoelectric Point: 10.0023
>AT107402 WP_078274722.1 NZ_CP030241:c100593-100312 [Moraxella bovis]
VQNEFYDDLKASLTEALAIAKGEISPSRTFTYERPNIKDIRAKTGLSQTQFAQKLHISPKTLKNWEQGIRTPTGPAITLI
RLLDKNPDLISMA
VQNEFYDDLKASLTEALAIAKGEISPSRTFTYERPNIKDIRAKTGLSQTQFAQKLHISPKTLKNWEQGIRTPTGPAITLI
RLLDKNPDLISMA
Download Length: 282 bp
>AT107402 NZ_CP030241:c100593-100312 [Moraxella bovis]
GTGCAAAATGAGTTTTACGATGATTTAAAAGCCTCATTGACTGAGGCTCTGGCAATCGCTAAGGGCGAAATTTCCCCAAG
TCGTACATTCACTTATGAACGCCCAAACATCAAAGATATTCGGGCAAAAACAGGGCTATCACAAACCCAGTTCGCCCAGA
AGCTACACATAAGCCCTAAAACGCTTAAAAACTGGGAACAGGGCATTAGAACGCCAACAGGTCCAGCCATTACCCTAATT
AGATTACTTGACAAAAACCCTGATTTAATTAGCATGGCATAA
GTGCAAAATGAGTTTTACGATGATTTAAAAGCCTCATTGACTGAGGCTCTGGCAATCGCTAAGGGCGAAATTTCCCCAAG
TCGTACATTCACTTATGAACGCCCAAACATCAAAGATATTCGGGCAAAAACAGGGCTATCACAAACCCAGTTCGCCCAGA
AGCTACACATAAGCCCTAAAACGCTTAAAAACTGGGAACAGGGCATTAGAACGCCAACAGGTCCAGCCATTACCCTAATT
AGATTACTTGACAAAAACCCTGATTTAATTAGCATGGCATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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