Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 1261195..1261417 Replicon chromosome
Accession NZ_CP030240
Organism Escherichia coli strain ER1709

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag DQ225_RS06125 Protein ID WP_000141634.1
Coordinates 1261195..1261302 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 1261351..1261417 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQ225_RS06100 1256448..1257200 - 753 Protein_1186 cellulose biosynthesis protein BcsQ -
DQ225_RS06105 1257212..1257400 - 189 WP_001063318.1 YhjR family protein -
DQ225_RS06110 1257673..1259244 + 1572 WP_001204927.1 cellulose biosynthesis protein BcsE -
DQ225_RS06115 1259241..1259432 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
DQ225_RS06120 1259429..1261108 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
DQ225_RS06125 1261195..1261302 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 1261351..1261417 + 67 - - Antitoxin
DQ225_RS06130 1261778..1263049 + 1272 WP_001295225.1 transporter -
DQ225_RS06135 1263079..1264083 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
DQ225_RS06140 1264080..1265063 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
DQ225_RS06145 1265074..1265976 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T107367 WP_000141634.1 NZ_CP030240:c1261302-1261195 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T107367 NZ_CP030240:c1261302-1261195 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT107367 NZ_CP030240:1261351-1261417 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References