Detailed information of TA system TA107354

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/RelE-MqsA
• Location: 76104..76753
• Replicon: plasmid pSA20021456.1
• Accession: NZ_CP030220
• Organism: Salmonella enterica strain SA20021456

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: CHC34_RS26585
• Protein ID: WP_154708363.1
• Coordinates: 76415..76753 (-)
• Length: 113 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: CHC34_RS26580
• Protein ID: WP_023222688.1
• Coordinates: 76104..76415 (-)
• Length: 104 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHC34_RS26550	71142..71516	-	375	WP_023222683.1	type IV conjugative transfer system pilin TraA	-
CHC34_RS26555	71589..71771	-	183	WP_024147741.1	conjugal transfer relaxosome protein TraY	-
CHC34_RS26560	72681..73067	-	387	WP_023222684.1	relaxosome protein TraM	-
CHC34_RS26565	73482..73952	+	471	WP_023222685.1	transglycosylase SLT domain-containing protein	-
CHC34_RS26570	74272..75093	-	822	WP_023222686.1	DUF945 domain-containing protein	-
CHC34_RS26575	75198..75422	-	225	WP_023222687.1	hypothetical protein	-
CHC34_RS26580	76104..76415	-	312	WP_023222688.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
CHC34_RS26585	76415..76753	-	339	WP_154708363.1	toxin	Toxin
CHC34_RS26590	76883..77038	-	156	WP_023222690.1	hypothetical protein	-
CHC34_RS26595	77086..77385	-	300	WP_023222691.1	hypothetical protein	-
CHC34_RS26600	78024..78185	-	162	WP_023222692.1	type I toxin-antitoxin system Hok family toxin	-
CHC34_RS26605	78401..78727	-	327	WP_023222694.1	hypothetical protein	-
CHC34_RS26610	78724..79452	-	729	WP_023222695.1	plasmid SOS inhibition protein A	-
CHC34_RS26615	79449..79883	-	435	WP_154808116.1	conjugation system SOS inhibitor PsiB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..159279	159279

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (23-64)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 113 a.a.
• Molecular weight: 16648.97 Da
• Isoelectric Point: 5.5500

>T107354 WP_154708363.1 NZ_CP030220:c76753-76415 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 339 bp

>T107354 NZ_CP030220:c76753-76415 [Salmonella enterica]
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Antitoxin

Protein

• Length: 104 a.a.
• Molecular weight: 15324.38 Da
• Isoelectric Point: 5.5500

>AT107354 WP_023222688.1 NZ_CP030220:c76415-76104 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 312 bp

>AT107354 NZ_CP030220:c76415-76104 [Salmonella enterica]
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