Detailed information of TA system TA107352

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/MqsA(antitoxin)
• Location: 89107..89758
• Replicon: plasmid pSA20075157.1
• Accession: NZ_CP030218
• Organism: Salmonella enterica strain SA20075157

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: CHD36_RS24570
• Protein ID: WP_000271343.1
• Coordinates: 89414..89758 (-)
• Length: 115 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: A0A2H4YPR7
• Locus tag: CHD36_RS24565
• Protein ID: WP_000166615.1
• Coordinates: 89107..89421 (-)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHD36_RS24535	84577..84828	+	252	WP_000125517.1	hypothetical protein	-
CHD36_RS24540	84821..85405	+	585	WP_000040823.1	conjugal transfer protein TraX	-
CHD36_RS24545	85504..87675	+	2172	WP_000691666.1	DotA/TraY family protein	-
CHD36_RS24550	87750..88364	+	615	Protein_95	plasmid IncI1-type surface exclusion protein ExcA	-
CHD36_RS24555	88436..88642	-	207	WP_000062605.1	HEAT repeat domain-containing protein	-
CHD36_RS24560	88788..88940	-	153	WP_024134926.1	Hok/Gef family protein	-
CHD36_RS24565	89107..89421	-	315	WP_000166615.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
CHD36_RS24570	89414..89758	-	345	WP_000271343.1	hypothetical protein	Toxin
CHD36_RS24575	89906..91114	+	1209	WP_000122819.1	IncI1-type conjugal transfer protein TrbA	-
CHD36_RS24580	91132..92208	+	1077	WP_000188938.1	DsbC family protein	-
CHD36_RS24585	92201..94492	+	2292	WP_024134927.1	TraM recognition domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..97234	97234

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin CcdB (2-100)

Antitoxin

• Post-segregation antitoxin CcdA (2-72)

Sequences

Toxin

Protein

• Length: 115 a.a.
• Molecular weight: 16943.32 Da
• Isoelectric Point: 5.5500

>T107352 WP_000271343.1 NZ_CP030218:c89758-89414 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 345 bp

>T107352 NZ_CP030218:c89758-89414 [Salmonella enterica]
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Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 15471.56 Da
• Isoelectric Point: 5.5500

>AT107352 WP_000166615.1 NZ_CP030218:c89421-89107 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 315 bp

>AT107352 NZ_CP030218:c89421-89107 [Salmonella enterica]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Structures

Antitoxin

• AlphaFold DB: A0A2H4YPR7