Detailed information of TA system TA107345

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/COG4683-HTH_37
• Location: 8725..9372
• Replicon: plasmid pSA20083530.2
• Accession: NZ_CP030205
• Organism: Salmonella enterica strain SA20083530

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: CHD70_RS27695
• Protein ID: WP_162803275.1
• Coordinates: 8725..9066 (+)
• Length: 114 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: CHD70_RS27700
• Protein ID: WP_114047696.1
• Coordinates: 9073..9372 (+)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHD70_RS27655	3821..3898	-	78	WP_114047710.1	RepA leader peptide Tap	-
CHD70_RS27665	4134..4389	-	256	Protein_4	replication regulatory protein RepA	-
CHD70_RS27675	5081..6306	+	1226	Protein_5	IS91 family transposase	-
CHD70_RS27685	7246..7530	-	285	WP_114047694.1	stability/ partitioning determinant	-
CHD70_RS27690	7620..8282	-	663	WP_114047695.1	P-loop NTPase	-
CHD70_RS27695	8725..9066	+	342	WP_162803275.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CHD70_RS27700	9073..9372	+	300	WP_114047696.1	XRE family transcriptional regulator	Antitoxin
CHD70_RS27705	9423..10088	-	666	Protein_10	hypothetical protein	-
CHD70_RS27710	10300..10925	+	626	Protein_11	ArdC family protein	-
CHD70_RS27715	11218..12240	-	1023	WP_114047697.1	IS110 family transposase	-
CHD70_RS27725	12893..13147	-	255	WP_162803276.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..33467	33467

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (9-108)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 14629.86 Da
• Isoelectric Point: 12.8531

>T107345 WP_162803275.1 NZ_CP030205:8725-9066 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 342 bp

>T107345 NZ_CP030205:8725-9066 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 12835.43 Da
• Isoelectric Point: 12.7956

>AT107345 WP_114047696.1 NZ_CP030205:9073-9372 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 300 bp

>AT107345 NZ_CP030205:9073-9372 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA