Detailed information of TA system TA107335

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 52046..52548
• Replicon: plasmid pIncFII.2
• Accession: NZ_CP030177
• Organism: Salmonella enterica subsp. enterica serovar Milwaukee str. SA19950795

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: LFZ28_RS25870
• Protein ID: WP_058108457.1
• Coordinates: 52046..52300 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: LFZ28_RS25875
• Protein ID: WP_058108458.1
• Coordinates: 52297..52548 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LFZ28_RS25845	47946..48863	+	918	WP_058108452.1	hypothetical protein	-
LFZ28_RS25850	48986..49837	+	852	WP_162802314.1	hypothetical protein	-
LFZ28_RS25855	49862..51007	+	1146	WP_058108454.1	hypothetical protein	-
LFZ28_RS25860	51017..51496	+	480	WP_058108455.1	type III secretion system chaperone	-
LFZ28_RS25865	51484..51897	+	414	WP_058108456.1	type III secretion system chaperone	-
LFZ28_RS25870	52046..52300	-	255	WP_058108457.1	Txe/YoeB family addiction module toxin	Toxin
LFZ28_RS25875	52297..52548	-	252	WP_058108458.1	YoeB-YefM toxin-antitoxin system antitoxin YefM	Antitoxin
LFZ28_RS25880	52808..53158	-	351	WP_058108459.1	hypothetical protein	-
LFZ28_RS25890	55143..55583	+	441	WP_058108461.1	universal stress protein	-
LFZ28_RS26465	56511..57104	+	594	WP_162802315.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..131435	131435

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-92)

Antitoxin

• Antitoxin ParD (1-76)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 12528.03 Da
• Isoelectric Point: 5.5500

>T107335 WP_058108457.1 NZ_CP030177:c52300-52046 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFF

Nucleotide

• Length: 255 bp

>T107335 NZ_CP030177:c52300-52046 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
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Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 12380.85 Da
• Isoelectric Point: 5.5500

>AT107335 WP_058108458.1 NZ_CP030177:c52548-52297 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Nucleotide

• Length: 252 bp

>AT107335 NZ_CP030177:c52548-52297 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
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