Detailed information of TA system TA107332

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 49001..49503
• Replicon: plasmid pIncFII.1
• Accession: NZ_CP030176
• Organism: Salmonella enterica subsp. enterica serovar Milwaukee str. SA19950795

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: LFZ28_RS24975
• Protein ID: WP_058108457.1
• Coordinates: 49001..49255 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: LFZ28_RS24980
• Protein ID: WP_058108458.1
• Coordinates: 49252..49503 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LFZ28_RS24950	44901..45818	+	918	WP_058108452.1	hypothetical protein	-
LFZ28_RS24955	45941..46792	+	852	WP_162802314.1	hypothetical protein	-
LFZ28_RS24960	46817..47962	+	1146	WP_058108454.1	hypothetical protein	-
LFZ28_RS24965	47972..48451	+	480	WP_058108455.1	type III secretion system chaperone	-
LFZ28_RS24970	48439..48852	+	414	WP_058108456.1	type III secretion system chaperone	-
LFZ28_RS24975	49001..49255	-	255	WP_058108457.1	Txe/YoeB family addiction module toxin	Toxin
LFZ28_RS24980	49252..49503	-	252	WP_058108458.1	YoeB-YefM toxin-antitoxin system antitoxin YefM	Antitoxin
LFZ28_RS24985	49763..50113	-	351	WP_058108459.1	hypothetical protein	-
LFZ28_RS24995	52098..52538	+	441	WP_058108461.1	universal stress protein	-
LFZ28_RS26440	53466..54059	+	594	WP_162802315.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..148530	148530

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 12528.03 Da
• Isoelectric Point: 5.5500

>T107332 WP_058108457.1 NZ_CP030176:c49255-49001 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFF

Nucleotide

• Length: 255 bp

>T107332 NZ_CP030176:c49255-49001 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
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Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 12380.85 Da
• Isoelectric Point: 5.5500

>AT107332 WP_058108458.1 NZ_CP030176:c49503-49252 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Nucleotide

• Length: 252 bp

>AT107332 NZ_CP030176:c49503-49252 [Salmonella enterica subsp. enterica serovar Milwaukee str.]
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