107215

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2715699..2715883 Replicon chromosome
Accession NZ_CP030138
Organism Staphylococcus aureus strain M48

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag C2G36_RS14585 Protein ID WP_000482650.1
Coordinates 2715776..2715883 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2715699..2715759 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2G36_RS14560 2711229..2711396 - 168 WP_001790576.1 hypothetical protein -
C2G36_RS14570 2711627..2713360 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
C2G36_RS14575 2713385..2715148 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2715699..2715759 + 61 - - Antitoxin
C2G36_RS14585 2715776..2715883 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
C2G36_RS14590 2716017..2716403 - 387 WP_000779358.1 flippase GtxA -
C2G36_RS14595 2716671..2717813 + 1143 WP_001176863.1 glycerate kinase -
C2G36_RS14600 2717873..2718532 + 660 WP_000831298.1 membrane protein -
C2G36_RS14605 2718714..2719925 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
C2G36_RS14610 2720048..2720521 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T107215 WP_000482650.1 NZ_CP030138:c2715883-2715776 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T107215 NZ_CP030138:c2715883-2715776 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT107215 NZ_CP030138:2715699-2715759 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References