107213

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2425612..2425829 Replicon chromosome
Accession NZ_CP030138
Organism Staphylococcus aureus strain M48

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag C2G36_RS12985 Protein ID WP_001802298.1
Coordinates 2425725..2425829 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2425612..2425667 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2G36_RS12965 2421749..2422414 - 666 WP_001024094.1 SDR family oxidoreductase -
C2G36_RS12970 2422566..2422886 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
C2G36_RS12975 2422888..2423868 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
C2G36_RS12980 2424134..2425225 + 1092 WP_000495671.1 lytic regulatory protein -
- 2425612..2425667 + 56 - - Antitoxin
C2G36_RS12985 2425725..2425829 - 105 WP_001802298.1 hypothetical protein Toxin
C2G36_RS16325 2425990..2426473 - 484 Protein_2410 recombinase family protein -
C2G36_RS12995 2426516..2427652 - 1137 WP_000115564.1 SAP domain-containing protein -
C2G36_RS13000 2427941..2428033 + 93 WP_001790138.1 hypothetical protein -
C2G36_RS13005 2428738..2429438 - 701 Protein_2413 HAD family phosphatase -
C2G36_RS13010 2429506..2430288 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T107213 WP_001802298.1 NZ_CP030138:c2425829-2425725 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T107213 NZ_CP030138:c2425829-2425725 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT107213 NZ_CP030138:2425612-2425667 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References