Detailed information of TA system TA107199

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1917667..1917849
• Replicon: chromosome
• Accession: NZ_CP030138
• Organism: Staphylococcus aureus strain M48

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: C2G36_RS09785
• Protein ID: WP_001801861.1
• Coordinates: 1917667..1917762 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1917790..1917849 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C2G36_RS09735	1913327..1913953	+	627	WP_000669046.1	hypothetical protein	-
C2G36_RS09740	1913994..1914338	+	345	WP_000627551.1	DUF3969 family protein	-
C2G36_RS09745	1914436..1914987	+	552	WP_000414205.1	hypothetical protein	-
C2G36_RS09750	1915205..1915846	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
C2G36_RS09755	1915960..1916145	-	186	WP_000809857.1	hypothetical protein	-
C2G36_RS09760	1916147..1916323	-	177	WP_000375476.1	hypothetical protein	-
C2G36_RS09765	1916334..1916717	-	384	WP_000070811.1	hypothetical protein	-
C2G36_RS09775	1917321..1917464	-	144	WP_001549059.1	transposase	-
C2G36_RS09785	1917667..1917762	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1917790..1917849	-	60	-	-	Antitoxin
C2G36_RS09790	1917885..1917986	+	102	WP_001791893.1	hypothetical protein	-
C2G36_RS09795	1917964..1918140	-	177	Protein_1839	transposase	-
C2G36_RS09800	1918334..1918711	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (2-108)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T107199 WP_001801861.1 NZ_CP030138:1917667-1917762 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T107199 NZ_CP030138:1917667-1917762 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT107199 NZ_CP030138:c1917849-1917790 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin