Detailed information of TA system TA107194

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 922634..922816
• Replicon: chromosome
• Accession: NZ_CP030137
• Organism: Staphylococcus aureus strain M51

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: C2G35_RS05200
• Protein ID: WP_001801861.1
• Coordinates: 922721..922816 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	922634..922693 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C2G35_RS05185	921772..922149	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
C2G35_RS05190	922343..922519	+	177	Protein_928	transposase	-
C2G35_RS05195	922497..922598	-	102	WP_001791893.1	hypothetical protein	-
-	922634..922693	+	60	-	-	Antitoxin
C2G35_RS05200	922721..922816	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
C2G35_RS05210	923019..923162	+	144	WP_001549059.1	transposase	-
C2G35_RS05220	923766..924149	+	384	WP_000070811.1	hypothetical protein	-
C2G35_RS05225	924160..924336	+	177	WP_000375476.1	hypothetical protein	-
C2G35_RS05230	924338..924523	+	186	WP_000809857.1	hypothetical protein	-
C2G35_RS05235	924637..925278	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
C2G35_RS05240	925496..926047	-	552	WP_000414205.1	hypothetical protein	-
C2G35_RS05245	926145..926489	-	345	WP_000627551.1	DUF3969 family protein	-
C2G35_RS05250	926530..927156	-	627	WP_129364309.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	904114..948842	44728

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T107194 WP_001801861.1 NZ_CP030137:c922816-922721 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T107194 NZ_CP030137:c922816-922721 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT107194 NZ_CP030137:922634-922693 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGTTAGTGAGGGG

Structures

Antitoxin