Detailed information of TA system TA107177

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 936741..936921
• Replicon: chromosome
• Accession: NZ_CP030136
• Organism: Staphylococcus aureus strain S57

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CHN55_RS05245
• Protein ID: WP_001801861.1
• Coordinates: 936826..936921 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	936741..936798 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHN55_RS05225	932316..932996	+	681	Protein_935	DNA adenine methylase	-
CHN55_RS05230	933048..934220	-	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
CHN55_RS05240	934480..936175	+	1696	Protein_937	hypothetical protein	-
-	936741..936798	+	58	-	-	Antitoxin
CHN55_RS05245	936826..936921	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
CHN55_RS05255	937373..937819	+	447	WP_000747805.1	DUF1433 domain-containing protein	-
CHN55_RS05260	938003..938559	+	557	Protein_940	ImmA/IrrE family metallo-endopeptidase	-
CHN55_RS05265	938691..939443	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
CHN55_RS05270	939470..940213	-	744	WP_175393121.1	exotoxin	-
CHN55_RS05275	940240..940866	-	627	WP_000669028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	914125..943425	29300
	-	flank	IS/Tn	-	-	933048..934220	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T107177 WP_001801861.1 NZ_CP030136:c936921-936826 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T107177 NZ_CP030136:c936921-936826 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT107177 NZ_CP030136:936741-936798 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin