Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 3047849..3048460 Replicon chromosome
Accession NZ_CP030053
Organism Bradyrhizobium guangzhouense strain CCBAU 51670

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag XH91_RS14675 Protein ID WP_128951236.1
Coordinates 3047849..3048133 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag XH91_RS14680 Protein ID WP_128951237.1
Coordinates 3048143..3048460 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH91_RS14660 3043109..3044740 - 1632 WP_164934077.1 OprO/OprP family phosphate-selective porin -
XH91_RS14665 3045057..3046463 + 1407 WP_164934076.1 DegQ family serine endoprotease -
XH91_RS14670 3046460..3047794 + 1335 WP_128951235.1 replication-associated recombination protein A -
XH91_RS14675 3047849..3048133 + 285 WP_128951236.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XH91_RS14680 3048143..3048460 + 318 WP_128951237.1 HigA family addiction module antidote protein Antitoxin
XH91_RS14685 3048457..3049671 + 1215 WP_128951238.1 RluA family pseudouridine synthase -
XH91_RS14690 3049797..3050243 - 447 WP_128951239.1 hypothetical protein -
XH91_RS14695 3050320..3051114 + 795 WP_128951240.1 ATPase -
XH91_RS14705 3051170..3052813 + 1644 WP_164934075.1 flagellar hook-length control protein FliK -
XH91_RS14710 3052810..3053073 + 264 WP_074117543.1 EscU/YscU/HrcU family type III secretion system export apparatus switch protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10355.53 Da        Isoelectric Point: 5.6907

>T106958 WP_128951236.1 NZ_CP030053:3047849-3048133 [Bradyrhizobium guangzhouense]
MIVSYGDKRTERFAAGQHVKEFSGFARQAETRLDRLDAATGPADLAALPGNRFEALKGDRAGRFSIGTSDQWRICFGWPE
GSPGPIDVEIVDYH

Download         Length: 285 bp

>T106958 NZ_CP030053:3047849-3048133 [Bradyrhizobium guangzhouense]
ATGATCGTCAGCTACGGCGACAAGCGCACCGAGCGATTTGCCGCTGGCCAGCACGTCAAGGAATTCTCGGGATTTGCTCG
GCAGGCAGAGACGCGCCTCGATAGATTGGACGCGGCAACCGGTCCGGCCGATTTGGCGGCACTGCCTGGTAATCGATTTG
AAGCCTTGAAGGGCGATCGCGCTGGACGGTTCTCGATTGGGACCAGCGATCAATGGCGGATCTGCTTCGGATGGCCGGAG
GGATCGCCCGGTCCAATTGATGTAGAGATCGTCGACTATCACTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11672.32 Da        Isoelectric Point: 10.5812

>AT106958 WP_128951237.1 NZ_CP030053:3048143-3048460 [Bradyrhizobium guangzhouense]
MPRTPIHPGEQLAEELRELGITAAELSRQLDVPVNRITGIINGQRGITADTALRLGHWFGTSPQFWMNLQQQYELRLAEK
EVGAQVASLPRRANAQSTRKLGKTA

Download         Length: 318 bp

>AT106958 NZ_CP030053:3048143-3048460 [Bradyrhizobium guangzhouense]
ATGCCCCGCACGCCCATTCATCCCGGCGAACAGCTTGCCGAAGAGCTGCGCGAACTCGGCATCACGGCCGCGGAGTTGTC
GCGTCAGCTCGACGTACCCGTGAATCGCATCACGGGCATCATCAACGGTCAGCGGGGCATTACGGCCGATACGGCACTTC
GTCTTGGTCACTGGTTCGGCACGAGCCCACAGTTCTGGATGAACCTTCAACAACAATATGAGCTGCGGCTGGCGGAAAAG
GAGGTTGGCGCGCAGGTTGCGTCGCTGCCCCGCCGTGCCAACGCGCAGTCGACACGAAAGCTTGGAAAAACAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References