Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_31
Location 1011965..1012635 Replicon chromosome
Accession NZ_CP030053
Organism Bradyrhizobium guangzhouense strain CCBAU 51670

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag XH91_RS04930 Protein ID WP_128949535.1
Coordinates 1012312..1012635 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag XH91_RS04925 Protein ID WP_128949534.1
Coordinates 1011965..1012246 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH91_RS04910 1007739..1008674 - 936 WP_128949531.1 sensor domain-containing diguanylate cyclase -
XH91_RS04915 1008813..1010480 - 1668 WP_128949532.1 tetratricopeptide repeat-containing glycosyltransferase family protein -
XH91_RS04920 1010687..1011784 - 1098 WP_128949533.1 glycoside hydrolase family 3 protein -
XH91_RS04925 1011965..1012246 - 282 WP_128949534.1 helix-turn-helix domain-containing protein Antitoxin
XH91_RS04930 1012312..1012635 - 324 WP_128949535.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XH91_RS04935 1012713..1014023 - 1311 WP_128949536.1 MFS transporter -
XH91_RS04940 1014123..1014719 + 597 WP_128949537.1 TetR/AcrR family transcriptional regulator -
XH91_RS38690 1014891..1015061 + 171 WP_164934285.1 hypothetical protein -
XH91_RS04945 1015149..1016171 - 1023 WP_128949538.1 LLM class flavin-dependent oxidoreductase -
XH91_RS04950 1016202..1017173 - 972 WP_128949539.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-83)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12059.10 Da        Isoelectric Point: 11.0680

>T106956 WP_128949535.1 NZ_CP030053:c1012635-1012312 [Bradyrhizobium guangzhouense]
VHWRVEILNETVVAEIAALPADMQARFLRLAERIASTGLEGLGEPHVKHLEGKLWELRLTGRDGIARALYVTAIGRRVVV
VRAFVKKTQRTPRAEIELALRRANEIT

Download         Length: 324 bp

>T106956 NZ_CP030053:c1012635-1012312 [Bradyrhizobium guangzhouense]
GTGCACTGGCGAGTTGAAATCCTCAACGAAACCGTTGTCGCGGAGATAGCTGCCCTGCCGGCCGACATGCAGGCGCGCTT
TCTGCGGCTTGCGGAGCGCATTGCCTCGACCGGCCTGGAAGGCTTGGGCGAACCGCACGTCAAGCACCTTGAAGGGAAGC
TTTGGGAGCTACGACTGACAGGGCGCGACGGAATTGCCCGTGCCCTCTACGTCACCGCGATCGGTCGGAGAGTTGTCGTC
GTGCGCGCGTTTGTGAAGAAGACGCAAAGGACCCCACGCGCGGAGATCGAACTCGCCCTACGGAGAGCAAATGAGATCAC
GTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10169.78 Da        Isoelectric Point: 10.8350

>AT106956 WP_128949534.1 NZ_CP030053:c1012246-1011965 [Bradyrhizobium guangzhouense]
MTIPFDKLKARLLANPKVKAEYDALAPEFEIAAELLKARLRAGFSQSELAARMGTSQSTIARLESGQTLPSTKTLLRYAE
ATGSRFRVRLSAA

Download         Length: 282 bp

>AT106956 NZ_CP030053:c1012246-1011965 [Bradyrhizobium guangzhouense]
ATGACAATTCCATTCGACAAGCTCAAGGCTCGTCTCCTGGCCAACCCGAAGGTCAAGGCCGAGTATGACGCACTCGCCCC
GGAATTCGAGATCGCTGCCGAATTGCTGAAGGCGCGCTTGCGGGCCGGATTCTCGCAGTCCGAGTTGGCTGCGCGAATGG
GTACCAGCCAGTCCACGATTGCCCGGCTTGAAAGCGGACAAACGCTGCCGAGCACAAAGACTCTTTTGCGCTATGCCGAG
GCGACCGGCAGCAGGTTCCGGGTGCGGCTCTCGGCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References