Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_31
Location 828832..829492 Replicon chromosome
Accession NZ_CP030048
Organism Bradyrhizobium sp. CCBAU 53338

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag XH90_RS03975 Protein ID WP_194479309.1
Coordinates 829169..829492 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag XH90_RS03970 Protein ID WP_194479308.1
Coordinates 828832..829113 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH90_RS03945 824147..824281 - 135 WP_008542748.1 50S ribosomal protein L34 -
XH90_RS03950 824642..826171 + 1530 WP_194479305.1 HAMP domain-containing histidine kinase -
XH90_RS03960 826489..827430 - 942 WP_194479306.1 sensor domain-containing diguanylate cyclase -
XH90_RS03965 827561..828658 - 1098 WP_194479307.1 glycoside hydrolase family 3 protein -
XH90_RS03970 828832..829113 - 282 WP_194479308.1 helix-turn-helix domain-containing protein Antitoxin
XH90_RS03975 829169..829492 - 324 WP_194479309.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XH90_RS03980 829581..830876 - 1296 WP_194479310.1 MFS transporter -
XH90_RS03985 830965..831561 + 597 WP_194479311.1 TetR/AcrR family transcriptional regulator -
XH90_RS03990 831811..832833 - 1023 WP_194479312.1 LLM class flavin-dependent oxidoreductase -
XH90_RS03995 833182..833475 + 294 WP_194479313.1 DUF718 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-83)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11977.04 Da        Isoelectric Point: 10.9084

>T106950 WP_194479309.1 NZ_CP030048:c829492-829169 [Bradyrhizobium sp. CCBAU 53338]
VPWRVDILNETVVAEIAALPADMQARFLRLAERIASTGLESLGEPHVKHLEGKLWELRLTGRDGIARALYVTAIGRRVVV
VRAFVKKTQKTPRAEIELALRRANEIA

Download         Length: 324 bp

>T106950 NZ_CP030048:c829492-829169 [Bradyrhizobium sp. CCBAU 53338]
GTGCCCTGGCGAGTTGACATCCTCAACGAAACGGTTGTCGCGGAGATAGCTGCCCTGCCGGCCGACATGCAGGCGCGTTT
TCTGCGGCTTGCTGAGCGCATTGCCTCGACCGGCTTGGAAAGCCTGGGCGAACCGCACGTCAAGCACCTTGAAGGGAAGC
TGTGGGAGCTACGGCTAACAGGGCGCGACGGAATTGCCCGTGCCCTCTACGTCACCGCGATCGGTCGGAGAGTTGTCGTC
GTGCGCGCGTTTGTGAAGAAGACGCAAAAGACCCCACGCGCGGAGATCGAACTCGCTCTACGGAGAGCAAATGAGATCGC
ATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10197.84 Da        Isoelectric Point: 10.8350

>AT106950 WP_194479308.1 NZ_CP030048:c829113-828832 [Bradyrhizobium sp. CCBAU 53338]
MTIPFDKLKARLLANPKVKAEYDALAPEFEIAAELLRARLRAGFSQSELAVRMGTSQSTIARLESGQTLPSTKTLLRYAE
ATGSKFRVRLSAA

Download         Length: 282 bp

>AT106950 NZ_CP030048:c829113-828832 [Bradyrhizobium sp. CCBAU 53338]
ATGACGATTCCATTCGACAAGCTCAAGGCTCGCCTTCTGGCCAACCCGAAGGTCAAGGCCGAGTATGACGCGCTCGCTCC
TGAATTCGAGATCGCCGCTGAATTGCTGAGAGCGCGCTTGCGGGCTGGGTTCTCGCAGTCCGAGTTGGCTGTGCGAATGG
GCACCAGCCAGTCCACGATCGCCCGGCTTGAAAGCGGGCAAACGCTACCGAGCACAAAAACACTTCTGCGCTATGCCGAG
GCAACCGGCAGCAAGTTCCGGGTACGACTCTCGGCGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References