Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2713980..2714306 | Replicon | chromosome |
Accession | NZ_CP030045 | ||
Organism | Enterococcus faecalis strain C54 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | A0A3N3Z2N6 |
Locus tag | DOU32_RS13860 | Protein ID | WP_073340360.1 |
Coordinates | 2714166..2714306 (+) | Length | 47 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2713980..2714164 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DOU32_RS13830 | 2709019..2709234 | - | 216 | WP_002354768.1 | zinc ribbon domain-containing protein | - |
DOU32_RS13835 | 2709373..2710365 | + | 993 | WP_002358973.1 | biotin--[acetyl-CoA-carboxylase] ligase | - |
DOU32_RS13840 | 2710629..2711267 | - | 639 | WP_073438309.1 | lytic polysaccharide monooxygenase | - |
DOU32_RS13850 | 2711953..2713569 | + | 1617 | WP_002406969.1 | phosphatase PAP2/LCP family protein | - |
DOU32_RS13855 | 2713898..2714047 | + | 150 | WP_002411240.1 | putative holin-like toxin | - |
- | 2713980..2714164 | - | 185 | NuclAT_9 | - | Antitoxin |
- | 2714021..2714164 | - | 144 | NuclAT_11 | - | - |
DOU32_RS13860 | 2714166..2714306 | + | 141 | WP_073340360.1 | putative holin-like toxin | Toxin |
- | 2714239..2714440 | - | 202 | NuclAT_7 | - | - |
DOU32_RS13865 | 2714537..2714680 | + | 144 | WP_073437820.1 | putative holin-like toxin | - |
- | 2714612..2714874 | - | 263 | NuclAT_10 | - | - |
- | 2714824..2714873 | + | 50 | NuclAT_13 | - | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 47 a.a. Molecular weight: 5218.33 Da Isoelectric Point: 10.3265
>T106934 WP_073340360.1 NZ_CP030045:2714166-2714306 [Enterococcus faecalis]
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDKKK
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDKKK
Download Length: 141 bp
>T106934 NZ_CP030045:2714166-2714306 [Enterococcus faecalis]
ATTTCTCTGAAAAATACGAATAAAAATATCGTTTACTGTACAACATATGAAACAATTCAGACGATCCTAGGGTTTGGTAT
GTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA
ATTTCTCTGAAAAATACGAATAAAAATATCGTTTACTGTACAACATATGAAACAATTCAGACGATCCTAGGGTTTGGTAT
GTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA
Antitoxin
Download Length: 185 bp
>AT106934 NZ_CP030045:c2714164-2713980 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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