Detailed information of TA system TA106902

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 113059..113399
• Replicon: chromosome
• Accession: NZ_CP030042
• Organism: Enterococcus faecalis strain C25

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: DOU31_RS00550
• Protein ID: WP_138807026.1
• Coordinates: 113247..113399 (-)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	113059..113314 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DOU31_RS00540	108540..108683	-	144	WP_002396786.1	putative holin-like toxin	-
-	108794..108927	+	134	-	-	-
DOU31_RS00545	109278..113057	+	3780	WP_010818049.1	WxL domain-containing protein	-
-	113059..113314	+	256	-	-	Antitoxin
-	113247..113399	-	153	-	-	Toxin
DOU31_RS00550	113247..113399	-	153	WP_138807026.1	putative holin-like toxin	Toxin
DOU31_RS00555	113660..115276	-	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
DOU31_RS00565	115960..116598	+	639	WP_002378863.1	lytic polysaccharide monooxygenase	-
DOU31_RS00570	116765..117757	-	993	WP_002398510.1	biotin--[acetyl-CoA-carboxylase] ligase	-
DOU31_RS00575	117896..118111	+	216	WP_002354768.1	zinc ribbon domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (17-50)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5679.98 Da
• Isoelectric Point: 11.0942

>T106902 WP_138807026.1 NZ_CP030042:c113399-113247 [Enterococcus faecalis]
VVRMSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALILKLLKNDKKK

Nucleotide

• Length: 153 bp

>T106902 NZ_CP030042:c113399-113247 [Enterococcus faecalis]
GTGGTGCGTATGAGCGTACTTCCAAAATTTACAGAAAGGAGAGGCCTTTTGTCAGCATATGAGACAATTCAGACGATTCT
AGGTTTTGGTATGTTTACCATTGCTTTGATTGCGCTGATTTTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin

Nucleotide

• Length: 256 bp

>AT106902 NZ_CP030042:113059-113314 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTTGAAATAGGAGGCTCAGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAATGA
TAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGTGTTAATTATTTAAA
AATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCAAAATCAGCGCAATCAAAGCA
ATGGTAAACATACCAA

Structures

Antitoxin