Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_31
Location 807289..807890 Replicon chromosome
Accession NZ_CP030037
Organism Bradyrhizobium sp. CCBAU 51753

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag XH93_RS03735 Protein ID WP_139487171.1
Coordinates 807567..807890 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag XH93_RS03730 Protein ID WP_139487170.1
Coordinates 807289..807570 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH93_RS03690 803193..803693 + 501 WP_139487164.1 GTP-binding protein -
XH93_RS03695 804134..804541 + 408 WP_194472431.1 DUF3597 domain-containing protein -
XH93_RS03700 804633..804920 + 288 WP_139487165.1 hypothetical protein -
XH93_RS03705 804998..805417 + 420 WP_139487166.1 large conductance mechanosensitive channel protein MscL -
XH93_RS03710 805557..805739 + 183 WP_139487167.1 hypothetical protein -
XH93_RS03715 805820..806578 - 759 WP_194474980.1 class I SAM-dependent methyltransferase -
XH93_RS03720 806625..807089 - 465 WP_194472432.1 Rrf2 family transcriptional regulator -
XH93_RS03725 807107..807286 + 180 WP_194472433.1 hypothetical protein -
XH93_RS03730 807289..807570 - 282 WP_139487170.1 helix-turn-helix domain-containing protein Antitoxin
XH93_RS03735 807567..807890 - 324 WP_139487171.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XH93_RS03740 807949..809679 - 1731 WP_194472434.1 ATP-dependent Clp protease adaptor ClpS -
XH93_RS03745 810037..812379 + 2343 WP_194472435.1 mechanosensitive ion channel -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-83)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11888.99 Da        Isoelectric Point: 11.0226

>T106890 WP_139487171.1 NZ_CP030037:c807890-807567 [Bradyrhizobium sp. CCBAU 51753]
MSWRVEILNETVAAEIAALPVDMQARFLRLSERILAVGLENLGEPHVKHLTGKLWELRLTGRDGIARALYVTASGRRVVV
VRAFVKKTQKTPAAEIELALQRAKGFA

Download         Length: 324 bp

>T106890 NZ_CP030037:c807890-807567 [Bradyrhizobium sp. CCBAU 51753]
ATGTCTTGGCGCGTCGAGATTCTCAACGAGACCGTCGCAGCCGAGATCGCCGCGTTGCCGGTCGACATGCAGGCGCGTTT
CCTCCGCCTTTCTGAACGGATTCTTGCAGTCGGGCTGGAAAACCTGGGAGAACCACACGTCAAGCACTTGACGGGCAAGC
TTTGGGAGTTGCGGCTGACCGGGCGCGACGGAATCGCAAGGGCGCTCTACGTGACGGCCAGTGGCCGCCGCGTCGTAGTG
GTCCGAGCGTTCGTCAAGAAAACGCAGAAGACGCCGGCCGCTGAGATCGAGTTGGCGCTACAGCGGGCAAAAGGGTTCGC
ATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10407.13 Da        Isoelectric Point: 11.1747

>AT106890 WP_139487170.1 NZ_CP030037:c807570-807289 [Bradyrhizobium sp. CCBAU 51753]
MTIPFEKLKARLLANPKVKAEYDALAPEFEIATELLRARRRAKLSQSELAERMGTSQSTIARLESGQTLPSTKTLLRFAK
ATDSKFRIRLSAA

Download         Length: 282 bp

>AT106890 NZ_CP030037:c807570-807289 [Bradyrhizobium sp. CCBAU 51753]
ATGACCATTCCGTTCGAAAAGCTCAAGGCTCGCCTGTTGGCCAATCCCAAGGTCAAGGCCGAGTACGACGCGCTTGCGCC
CGAGTTCGAGATCGCCACTGAGCTGCTGAGAGCGCGGCGGCGGGCGAAACTGTCGCAGTCCGAACTGGCGGAGCGAATGG
GGACCAGCCAGTCCACCATCGCCCGCCTCGAAAGCGGCCAGACGCTTCCCAGCACCAAGACGCTGCTGCGCTTCGCCAAG
GCAACCGACAGCAAATTCCGCATCCGCCTCTCGGCGGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References