Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4326688..4327342 Replicon chromosome
Accession NZ_CP029983
Organism Pseudomonas sp. LG1E9

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DNK50_RS19675 Protein ID WP_112196970.1
Coordinates 4326688..4327038 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DNK50_RS19680 Protein ID WP_099587022.1
Coordinates 4327028..4327342 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DNK50_RS19665 4323446..4324978 + 1533 WP_003232072.1 NADH-quinone oxidoreductase subunit M -
DNK50_RS19670 4324986..4326449 + 1464 WP_099587021.1 NADH-quinone oxidoreductase subunit NuoN -
DNK50_RS19675 4326688..4327038 + 351 WP_112196970.1 toxin Toxin
DNK50_RS19680 4327028..4327342 + 315 WP_099587022.1 transcriptional regulator Antitoxin
DNK50_RS19685 4327408..4328160 - 753 WP_099587023.1 outer membrane beta-barrel protein -
DNK50_RS19690 4328284..4329123 - 840 WP_112195908.1 arylamine N-acetyltransferase -
DNK50_RS19695 4329244..4329480 + 237 WP_099587025.1 hypothetical protein -
DNK50_RS19700 4329526..4329726 - 201 WP_099587026.1 hypothetical protein -
DNK50_RS19705 4329739..4329918 - 180 WP_032889724.1 hypothetical protein -
DNK50_RS19710 4330052..4330573 + 522 WP_112195910.1 DUF3087 domain-containing protein -
DNK50_RS19715 4330575..4331696 - 1122 WP_112195912.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13817.70 Da        Isoelectric Point: 9.7549

>T106829 WP_112196970.1 NZ_CP029983:4326688-4327038 [Pseudomonas sp. LG1E9]
MDALFIELPAFERHRKDYLSDELFHGFQQELMKNPQAGDVIEGTGGLRKVRFVDERRNKGRRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLTPQHKKALKQMLDREIKARTHHET

Download         Length: 351 bp

>T106829 NZ_CP029983:4326688-4327038 [Pseudomonas sp. LG1E9]
ATGGATGCTCTATTTATCGAACTGCCAGCCTTCGAGCGTCATCGCAAGGACTATCTAAGCGACGAGCTTTTCCACGGTTT
TCAACAGGAGTTAATGAAGAATCCACAAGCGGGCGACGTGATTGAAGGAACAGGTGGGCTGCGAAAGGTCCGCTTCGTTG
ATGAGCGGCGAAACAAAGGCAGGCGCGGTGGCCTGCGGGTCATCTACTACTGGTGGTCGGGAGGTACGCAGTTCTGGTTA
TTCACGCTGTACGGCAAACACGAACAGGACGACCTGACACCACAACACAAGAAAGCCCTAAAACAGATGCTGGACAGGGA
AATCAAAGCGAGAACACATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11770.57 Da        Isoelectric Point: 10.6525

>AT106829 WP_099587022.1 NZ_CP029983:4327028-4327342 [Pseudomonas sp. LG1E9]
MKREIFSELVEGFDALADERQGKVTLRTHKVHLNKLAPLTAEEVIAVRQQLNLSRSVFALYLRTNTRTLENWEQGRAKPN
AQATTLIRLVARFPETVAQLAALS

Download         Length: 315 bp

>AT106829 NZ_CP029983:4327028-4327342 [Pseudomonas sp. LG1E9]
ATGAAACGTGAAATCTTTTCCGAACTGGTCGAAGGCTTCGACGCGCTTGCGGACGAACGCCAGGGCAAAGTCACCCTGCG
TACCCACAAGGTCCATCTCAACAAACTGGCGCCGCTGACCGCCGAAGAAGTCATCGCCGTGCGCCAGCAACTGAACCTTT
CACGGTCGGTGTTCGCCCTGTACCTGCGCACCAATACCCGTACGCTGGAAAACTGGGAACAAGGGCGGGCCAAGCCCAAT
GCACAGGCCACCACCTTGATCCGCCTGGTAGCGCGCTTCCCGGAAACCGTAGCGCAACTGGCGGCCTTGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References