Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 109573..110267 Replicon chromosome
Accession NZ_CP029829
Organism Azospirillum ramasamyi strain M2T2B2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DM194_RS00490 Protein ID WP_111065450.1
Coordinates 109908..110267 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DM194_RS00485 Protein ID WP_111065449.1
Coordinates 109573..109911 (-) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DM194_RS00480 106728..109421 + 2694 WP_111065448.1 pyruvate, phosphate dikinase -
DM194_RS00485 109573..109911 - 339 WP_111065449.1 XRE family transcriptional regulator Antitoxin
DM194_RS00490 109908..110267 - 360 WP_111065450.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DM194_RS27950 110340..110486 + 147 WP_162629935.1 hypothetical protein -
DM194_RS00500 110857..111030 - 174 WP_111065452.1 antitoxin -
DM194_RS00505 111290..112720 + 1431 WP_162629941.1 AIPR family protein -
DM194_RS00510 112669..113474 + 806 WP_111065387.1 IS5 family transposase -
DM194_RS00515 113718..114095 - 378 WP_111065454.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-107)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 12973.83 Da        Isoelectric Point: 10.6473

>T106743 WP_111065450.1 NZ_CP029829:c110267-109908 [Azospirillum ramasamyi]
MHTVLFHTAFAAEFRALPQAVRIDLAAAAKVLGERGPALGRPHVDTLNGSRHANMKELRFKSNGGVWRVAFAFDPKRNAV
VLVAGDKSGVSEKRFYASLIATADSRYDDHLSDLKGTKP

Download         Length: 360 bp

>T106743 NZ_CP029829:c110267-109908 [Azospirillum ramasamyi]
ATGCACACCGTTCTCTTCCACACCGCGTTCGCGGCCGAATTCCGGGCTCTGCCGCAAGCCGTGCGGATCGACCTCGCTGC
CGCAGCCAAGGTGCTTGGAGAGCGTGGCCCGGCGCTCGGCCGGCCCCATGTCGATACGTTGAACGGGTCCAGGCATGCGA
ACATGAAGGAATTGCGGTTCAAGTCGAATGGTGGCGTGTGGCGCGTCGCCTTTGCCTTCGACCCGAAGCGCAACGCCGTC
GTGCTGGTTGCCGGGGATAAAAGCGGGGTTTCGGAAAAGCGGTTCTACGCCTCGCTGATCGCCACCGCCGACAGCCGGTA
TGACGACCATCTCTCCGACCTGAAAGGAACCAAGCCATGA

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12183.85 Da        Isoelectric Point: 4.7147

>AT106743 WP_111065449.1 NZ_CP029829:c109911-109573 [Azospirillum ramasamyi]
MTATIPFDQILSEMTDDERAAVDARAAGMLAEIDGLAELRRLAELTQGQVAETLNVKQPTVHQIEKRTDLYLSTLRRFVE
AAGGELELRVSLPGRGAFKLTGIGELTSGSQR

Download         Length: 339 bp

>AT106743 NZ_CP029829:c109911-109573 [Azospirillum ramasamyi]
ATGACGGCGACGATCCCGTTCGACCAGATCCTCTCCGAGATGACCGACGACGAGCGCGCCGCAGTGGATGCACGGGCCGC
CGGGATGCTGGCCGAGATCGACGGATTGGCGGAATTGCGCCGGCTGGCGGAACTGACCCAGGGTCAGGTGGCCGAAACCC
TGAACGTGAAGCAGCCGACCGTCCACCAGATCGAAAAGCGAACCGACCTGTATCTGTCCACCCTGCGGCGCTTCGTGGAA
GCCGCGGGCGGGGAGTTGGAGTTGCGGGTTTCCCTGCCGGGAAGAGGGGCGTTCAAGCTGACGGGCATCGGCGAGTTGAC
CTCCGGTTCCCAGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References