Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2546088..2546272 Replicon chromosome
Accession NZ_CP029751
Organism Staphylococcus aureus strain Smith

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CFC57_RS13160 Protein ID WP_000482647.1
Coordinates 2546165..2546272 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2546088..2546148 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFC57_RS13145 2541542..2541709 - 168 WP_042906270.1 hypothetical protein -
CFC57_RS13150 2541940..2543673 - 1734 WP_115287583.1 ABC transporter ATP-binding protein/permease -
CFC57_RS13155 2543698..2545461 - 1764 WP_001064641.1 ABC transporter ATP-binding protein/permease -
- 2546088..2546148 + 61 - - Antitoxin
CFC57_RS13160 2546165..2546272 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
CFC57_RS13165 2546406..2546792 - 387 WP_000779353.1 flippase GtxA -
CFC57_RS13170 2547060..2548202 + 1143 WP_001176866.1 glycerate kinase -
CFC57_RS13175 2548262..2548921 + 660 WP_000831298.1 membrane protein -
CFC57_RS13180 2549104..2550315 + 1212 WP_001191926.1 multidrug effflux MFS transporter -
CFC57_RS13185 2550438..2550911 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T106720 WP_000482647.1 NZ_CP029751:c2546272-2546165 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T106720 NZ_CP029751:c2546272-2546165 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT106720 NZ_CP029751:2546088-2546148 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References