Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1920846..1921500 Replicon chromosome
Accession NZ_CP029693
Organism Pseudomonas putida strain JBC17

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DKY63_RS08745 Protein ID WP_110963745.1
Coordinates 1920846..1921196 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DKY63_RS08750 Protein ID WP_110963746.1
Coordinates 1921186..1921500 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DKY63_RS08735 1917593..1919125 + 1533 WP_110963743.1 NADH-quinone oxidoreductase subunit M -
DKY63_RS08740 1919133..1920596 + 1464 WP_110963744.1 NADH-quinone oxidoreductase subunit NuoN -
DKY63_RS08745 1920846..1921196 + 351 WP_110963745.1 toxin Toxin
DKY63_RS08750 1921186..1921500 + 315 WP_110963746.1 transcriptional regulator Antitoxin
DKY63_RS08755 1921728..1923470 - 1743 WP_110963747.1 ABC transporter substrate-binding protein -
DKY63_RS08760 1923518..1923790 - 273 WP_110963748.1 DUF2160 domain-containing protein -
DKY63_RS08765 1923801..1924601 - 801 WP_110963749.1 carbohydrate ABC transporter permease -
DKY63_RS08770 1924610..1925476 - 867 WP_110963750.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13958.80 Da        Isoelectric Point: 8.0097

>T106465 WP_110963745.1 NZ_CP029693:1920846-1921196 [Pseudomonas putida]
MDALFIELPLFQKHRDDYLDDDLFRSFQLELLQNPEAGDLIEGTGGLRKIRFCDQRRGKGKRSGLRVIYYWWSGFNQFWL
FTVYGKNEQDDLSPFQKKVFRQALDREIKTRSHYET

Download         Length: 351 bp

>T106465 NZ_CP029693:1920846-1921196 [Pseudomonas putida]
ATGGATGCTCTGTTCATTGAATTACCTTTGTTTCAAAAACATCGAGACGATTATCTGGACGACGATTTGTTTCGCAGCTT
TCAGTTGGAGTTGCTGCAGAACCCCGAAGCAGGCGATCTCATTGAGGGAACCGGCGGGCTGCGAAAAATTCGCTTCTGCG
ACCAACGAAGAGGTAAAGGCAAGCGCAGTGGCTTACGAGTAATTTACTACTGGTGGTCCGGCTTCAATCAATTCTGGCTG
TTCACTGTGTACGGCAAAAACGAGCAAGACGACCTGTCGCCCTTCCAGAAGAAAGTTTTCAGACAAGCACTGGATAGAGA
AATCAAAACGAGATCCCACTATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11970.85 Da        Isoelectric Point: 7.0150

>AT106465 WP_110963746.1 NZ_CP029693:1921186-1921500 [Pseudomonas putida]
MKRDIFAELMDGLEALADERQGKITLRTHKVQLPELMPITAEEVIAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEYLAALT

Download         Length: 315 bp

>AT106465 NZ_CP029693:1921186-1921500 [Pseudomonas putida]
ATGAAACGTGACATTTTTGCCGAACTGATGGATGGCCTCGAAGCCCTGGCCGATGAGCGCCAGGGCAAGATCACGCTGCG
AACCCACAAGGTTCAGTTGCCAGAACTGATGCCCATCACCGCCGAGGAAGTAATCGCCATCCGCCAACAGCTCAACCTCT
CCCGGTCGGTGTTTGCGATGTATCTGCGTACCAACACCCGAACACTGGAGAACTGGGAACAGGGGCGCGCAACGCCCAAT
GCCCAAGCCACGACTCTGATCCGTCTGGTCGAGCGTTTTCCACAGACGATCGAATATCTCGCAGCCCTGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References