Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2859050..2859234 Replicon chromosome
Accession NZ_CP029680
Organism Staphylococcus aureus strain AR_0215

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag CSB71_RS15225 Protein ID WP_000482652.1
Coordinates 2859050..2859157 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2859174..2859234 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB71_RS15200 2854412..2854885 + 474 WP_000456486.1 GyrI-like domain-containing protein -
CSB71_RS15205 2855008..2856219 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
CSB71_RS15210 2856401..2857060 - 660 WP_000831298.1 membrane protein -
CSB71_RS15215 2857120..2858262 - 1143 WP_001176863.1 glycerate kinase -
CSB71_RS15220 2858530..2858916 + 387 WP_000779360.1 flippase GtxA -
CSB71_RS15225 2859050..2859157 + 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2859174..2859234 - 61 - - Antitoxin
CSB71_RS15235 2859860..2861623 + 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
CSB71_RS15240 2861648..2863381 + 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
CSB71_RS15250 2863612..2863779 + 168 Protein_2805 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T106322 WP_000482652.1 NZ_CP029680:2859050-2859157 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T106322 NZ_CP029680:2859050-2859157 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT106322 NZ_CP029680:c2859234-2859174 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References