Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 234050..234312 Replicon chromosome
Accession NZ_CP029680
Organism Staphylococcus aureus strain AR_0215

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CSB71_RS01450 Protein ID WP_001802298.1
Coordinates 234050..234154 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 234149..234312 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB71_RS01425 230847..231629 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
CSB71_RS01430 231697..232554 + 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
CSB71_RS01440 233212..233370 - 159 WP_001792784.1 hypothetical protein -
CSB71_RS01450 234050..234154 + 105 WP_001802298.1 hypothetical protein Toxin
- 234149..234312 - 164 - - Antitoxin
CSB71_RS01455 234587..235678 - 1092 WP_000495669.1 hypothetical protein -
CSB71_RS01460 235944..236921 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
CSB71_RS01465 236923..237243 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSB71_RS01470 237395..238060 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T106304 WP_001802298.1 NZ_CP029680:234050-234154 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T106304 NZ_CP029680:234050-234154 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT106304 NZ_CP029680:c234312-234149 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References