Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2313139..2313356 Replicon chromosome
Accession NZ_CP029678
Organism Staphylococcus aureus strain AR_0216

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CSB72_RS12475 Protein ID WP_001802298.1
Coordinates 2313252..2313356 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2313139..2313194 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB72_RS12455 2309276..2309941 - 666 WP_110179730.1 SDR family oxidoreductase -
CSB72_RS12460 2310093..2310413 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSB72_RS12465 2310415..2311395 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CSB72_RS12470 2311661..2312752 + 1092 WP_000495671.1 lytic regulatory protein -
- 2313139..2313194 + 56 - - Antitoxin
CSB72_RS12475 2313252..2313356 - 105 WP_001802298.1 hypothetical protein Toxin
CSB72_RS15685 2313517..2314000 - 484 Protein_2270 recombinase family protein -
CSB72_RS12485 2314043..2315179 - 1137 WP_000115564.1 SAP domain-containing protein -
CSB72_RS12490 2315468..2315560 + 93 WP_001790138.1 hypothetical protein -
CSB72_RS12495 2316265..2317122 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
CSB72_RS12500 2317190..2317972 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T106299 WP_001802298.1 NZ_CP029678:c2313356-2313252 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T106299 NZ_CP029678:c2313356-2313252 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT106299 NZ_CP029678:2313139-2313194 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References